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BP333

Tobramycin

British Pharmacopoeia (BP) Reference Standard

Synonym(s):

Nebramycin Factor 6, O-[3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)]-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribohexopyranosyl-(1→4)]-2-deoxy-D-streptamine

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About This Item

Empirical Formula (Hill Notation):
C18H37N5O9
CAS Number:
32986-56-4
Molecular Weight:
467.51
NACRES:
NA.24
UNSPSC Code:
41116107
Beilstein/REAXYS Number:
1357507
MDL number:
MFCD00077885
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grade

pharmaceutical primary standard

API family

tobramycin

form

solid

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

storage temp.

2-8°C

SMILES string

NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O

InChI

1S/C18H37N5O9/c19-3-9-8(25)2-7(22)17(29-9)31-15-5(20)1-6(21)16(14(15)28)32-18-13(27)11(23)12(26)10(4-24)30-18/h5-18,24-28H,1-4,19-23H2/t5-,6+,7+,8-,9+,10+,11+,12+,13+,14-,15+,16-,17+,18+/m0/s1

InChI key

NLVFBUXFDBBNBW-SNGYORCQSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support

Application

Tobramycin BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Tobramycin and Dexamethasone Eye Drops, Suspension
  • Apramycin Premix
  • Tobramycin Inhalation Powder, Hard Capsule
  • Apramycin Sulfate
  • Tobramycin Nebuliser Solution
  • Tobramycin Oral Solution
  • Tobramycin Eye Drops
  • Tobramycin Injection
  • Tobramycin Sulfate
  • Apramycin Veterinary Oral Powder

    • Biochem/physiol Actions

    Tobramycin is an aminoglycoside.
    Mode of Action: Binds to 70S ribosomal subunit; inhibits translocation; elicits miscoding.
    Spectrum of Activity: Gram negative bacteria. Not effective against Enterococci.

    Packaging

    Unit quantity: 350 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    Other Notes

    Sales restrictions may apply.

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    pictograms

    Health hazard
    GHS08

    signalword

    Warning

    hcodes

    H361f

    Hazard Classifications

    Repr. 2

    Storage Class

    11 - Combustible Solids

    wgk

    WGK 3

    Regulatory Information

    涉药品监管产品

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