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C2360000

Clomipramine hydrochloride

for microbiological assay, European Pharmacopoeia (EP) Reference Standard

Synonym(s):

3-Chloro-10,11-dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine hydrochloride, Anafranil hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C19H23ClN2 · HCl
CAS Number:
17321-77-6
Molecular Weight:
351.31
NACRES:
NA.24
PubChem Substance ID:
329774996
UNSPSC Code:
41116107
MDL number:
MFCD00069234
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grade

pharmaceutical primary standard

API family

clomipramine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Cl.CN(C)CCCN1c2ccccc2CCc3ccc(Cl)cc13

InChI

1S/C19H23ClN2.ClH/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22;/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3;1H

InChI key

WIMWMKZEIBHDTH-UHFFFAOYSA-N

Gene Information

human ... SLC6A4(6532)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Clomipramine hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT SE 1 - STOT SE 3

target_organs

Central nervous system, Central nervous system,Cardiovascular

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable

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Diagnosis and treatment of canine separation anxiety and the use of clomipramine hydrochloride (clomicalm).
D F Horwitz
Journal of the American Animal Hospital Association, 36(2), 107-109 (2000-03-24)
Ruyi Xu et al.
Journal of chromatography. A, 1350, 15-22 (2014-05-28)
A fast and efficient method for the determination of tricyclic antidepressants using electro-enhanced solid phase microextraction (SPME) coupled to gas chromatography-mass spectrometry (GC-MS) has been developed. One advantage of this approach is that the mass transfer of target analytes from
Carina Bäcktorp et al.
Journal of pharmaceutical sciences, 104(4), 1409-1420 (2015-02-26)
We have developed a predictive method, based on quantum chemical calculations, that qualitatively predicts N-oxidation by hydrogen peroxides in drug structures. The method uses linear correlations of two complementary approaches to estimate the activation barrier without calculating it explicitly. This
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Global Trade Item Number

SKUGTIN
C236000004061833475706