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Merck
CN

D9680

1,4-Dithioerythritol

BioXtra, ≥99.0%

Synonym(s):

erythro-1,4-Dimercapto-2,3-butanediol, erythro-2,3-Dihydroxy-1,4-butanedithiol, Cleland’s reagent, DTE

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About This Item

Linear Formula:
HSCH2CH(OH)CH(OH)CH2SH
CAS Number:
Molecular Weight:
154.25
UNSPSC Code:
12161504
NACRES:
NA.31
PubChem Substance ID:
EC Number:
229-998-8
Beilstein/REAXYS Number:
1719756
MDL number:
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product line

BioXtra

Quality Level

assay

≥99.0%

form

powder

reaction suitability

reagent type: reductant

impurities

Insoluble matter, passes filter test, ≤0.0005% Phosphorus (P)

pH

4.5-6.5 (0.1 M in H2O)

mp

82-84 °C (lit.)

solubility

H2O: 0.1 M, clear, colorless

anion traces

sulfate (SO42-): ≤0.005%

cation traces

Al: ≤0.0005%, Ca: ≤0.001%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.05%, Mg: ≤0.0005%, Na: ≤0.005%, Pb: ≤0.001%, Zn: ≤0.001%

absorption

≤0.4 at 280 in H2O at 0.1 M, ≤0.6 at 260 in H2O at 0.1 M

storage temp.

2-8°C

SMILES string

O[C@@H](CS)[C@H](O)CS

InChI

1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4+

InChI key

VHJLVAABSRFDPM-ZXZARUISSA-N

Application

Reagent for maintaining −SH groups in the reduced state; quantitatively reduces disulfides.


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Sam John et al.
Current protocols in molecular biology, Chapter 27, Unit 21-Unit 21 (2013-07-04)
DNase I-seq is a global and high-resolution method that uses the nonspecific endonuclease DNase I to map chromatin accessibility. These accessible regions, designated as DNase I hypersensitive sites (DHSs), define the regulatory features, (e.g., promoters, enhancers, insulators, and locus control
Tanju Ceyhan et al.
Dalton transactions (Cambridge, England : 2003), 39(41), 9801-9814 (2010-09-18)
The phthalodinitrile derivative 3 was prepared by the reaction of 1,4-dithioerythritol 1 and 4-nitrophthalonitrile 2 in dry DMF as the solvent in the presence of K(2)CO(3) as the base by the method of nucleophilic substitution of an activated nitro group
Magali Wagner et al.
Journal of agricultural and food chemistry, 59(7), 3146-3154 (2011-03-05)
During pasta processing, structural changes of protein occur, due to changes in water content, mechanical energy input, and high temperature treatments. The present paper investigates the impact of successive and intense thermal treatments (high temperature drying, cooking, and overcooking) on



Global Trade Item Number

SKUGTIN
D9680-5G04061833610619
D9680-1G04061833590973