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Merck
CN

G5767

D-(+)-Glucose

ACS reagent

Synonym(s):

Dextrose

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About This Item

Empirical Formula (Hill Notation):
C6H12O6
CAS Number:
Molecular Weight:
180.16
PubChem Substance ID:
UNSPSC Code:
12352201
MDL number:
NACRES:
NA.21
EC Number:
200-075-1
Beilstein/REAXYS Number:
1724615
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biological source

wheat

grade

ACS reagent

form

powder

optical activity

[α]25/D +52.5 to +53.0°(lit.)

impurities

Starch, passes test, ≤0.002 meq/g Titratable acid, ≤0.005% Insoluble matter

ign. residue

≤0.02%

loss

≤0.2% loss on drying, 105°C

color

colorless

mp

150-152 °C (lit.)

anion traces

chloride (Cl-): ≤0.01%, sulfate, sulfite (as SO42-): ≤0.005%

cation traces

Fe: ≤5 ppm, heavy metals: ≤5 ppm (by ICP-OES)

storage temp.

room temp

SMILES string

OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1

InChI key

WQZGKKKJIJFFOK-DVKNGEFBSA-N

Gene Information

human ... PYGM(5837)

General description

D-glucose, an aldohexose, possesses four chiral carbon atoms. It is an important product obtained from starch hydrolyzed by acid and/or enzymes.

Application

D-(+)-Glucose has been used:
  • as a supplement in Dulbecco′s phosphate-buffered saline (DPBS) for standardized serum bactericidal assay (SBA) using human complement
  • as a component in 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES)-buffered Tyrode′s solution to treat the excised diaphragmatic specimens to assess the effect of osmolarity changes on the intrinsic lymphatic pumping mechanism
  • to study the effect of restoring circulating glucose content in insulin-responsive neurons of rats
  • for oral glucose tolerance tests (OGTTs)

Biochem/physiol Actions

Glucose, the universal energy source for all human cells, is the vital precursor for the production and conversion of several downstream carbohydrates. The uptake of glucose is a key indicator of cellular energy metabolism. Glucose infusion can block the release of oxytocin and vasopressin by insulin-induced hypoglycemia in humans.

Preparation Note

The material may produce a yellowish solution if prepared at a higher concentration than 2 g + 15mL.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.


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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Jashanpreet Kaur et al.
PloS one, 10(3), e0122354-e0122354 (2015-03-27)
Genotyping studies of Australian Scedosporium isolates have revealed the strong prevalence of a recently described species: Scedosporium aurantiacum. In addition to occurring in the environment, this fungus is also known to colonise the respiratory tracts of cystic fibrosis (CF) patients.
Lars P Bechmann et al.
Journal of hepatology, 56(4), 952-964 (2011-12-17)
It is widely known that the liver is a central organ in lipogenesis, gluconeogenesis and cholesterol metabolism. However, over the last decades, a variety of pathological conditions highlighted the importance of metabolic functions within the diseased liver. As observed in
N P Karikoski et al.
Veterinary pathology, 52(5), 945-956 (2014-09-19)
Laminitis in equids is a clinical syndrome usually associated with systemic disease. Endocrinopathies recently have been recognized as the most common cause of laminitis, with hyperinsulinemia playing a key role. Descriptions of laminitis-associated lesions have been confusing due to the



Global Trade Item Number

SKUGTIN
G5767-25G04061835545223
G5767-500G04061833638439
G5767-5KG04061835545230