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Merck
CN

H2766

Sodium 1-heptanesulfonate

Synonym(s):

1-Heptanesulfonic acid sodium salt

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About This Item

Linear Formula:
C7H15O3SNa
CAS Number:
Molecular Weight:
202.25
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12161900
EC Number:
245-210-5
MDL number:
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biological source

synthetic (oragnic)

Quality Level

description

anionic

form

powder

mol wt

202.25 g/mol

technique(s)

HPLC: suitable, LC/MS: suitable

impurities

<2.0% water (Karl Fischer)

mp

300  °C (572 °F)

solubility

H2O: ≥100 mg/mL

cation traces

Na: 10.8-12.0 % (w/v) (anhydrous)

SMILES string

[Na+].CCCCCCCS([O-])(=O)=O

InChI

1S/C7H16O3S.Na/c1-2-3-4-5-6-7-11(8,9)10;/h2-7H2,1H3,(H,8,9,10);/q;+1/p-1

InChI key

REFMEZARFCPESH-UHFFFAOYSA-M

General description

Sodium 1-heptanesulfonate belongs to the sodium alkylsulfonate group of surfactants. It has a -SO?3 head group with sodium and an alkyl chain attached to the head group. Sodium 1-heptanesulfonate has a critical micelle concentration value of 0.302 mol/dm3.
Sodium 1-heptanesulfonate, also known as sodium heptanesulfonate, is a versatile compound commonly used in lab experiments and biochemical research. It acts as an ion-pairing agent, surfactant, and buffer, playing a crucial role in various applications. In biochemistry, it helps with tasks like protein purification and nucleic acid separation by reducing surface tension for better mixing. It also serves as a chelating agent for metal ion analysis and acts as a buffer in biological experiments. Sodium 1-heptanesulfonate is a preferred choice in HPLC and high-performance capillary electrophoresis analyses, aiding in the separation of positively charged analytes in both organic and inorganic compounds, from pharmaceuticals to peptide research.

Application

Sodium 1-heptanesulfonate has been used as a component of the mobile phase buffer for preequilibration of high performance liquid chromatography column.
Ion-pairing reagent for HPLC, including analyses of peptides and proteins.

Biochem/physiol Actions

Sodium 1-heptanesulfonate serves as an ion-pairing reagent for analysis of epinephrine and norepinephrine in ion-pairing chromatography (IPC).

Features and Benefits

  • Ideal for Cell Biology and Biochemical Research
  • High purity chemical suitable for multiple research applications

Other Notes

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Storage Class

11 - Combustible Solids

ppe

Eyeshields, Gloves, type N95 (US)



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Validated HPLC-Fl method for the analysis of S-adenosylmethionine and S-adenosylhomocysteine biomarkers in human blood
Albu C, et al.
Journal of Fluorescence, 23(3), 381-386 (2013)
Determination of S-adenosylmethionine and S-adenosylhomocysteine from human blood samples by HPLC-FL
Birsan C, et al.
Analytical Letters, 41(10), 1720-1731 (2008)
Analysis of catecholamines in urine by unique LC/MS suitable ion-pairing chromatography
Bergmann ML, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 1057(2), 118-123 (2017)



Global Trade Item Number

SKUGTIN
H2766-5G04061835545469
H2766-100G04061835545445
H2766-25G04061835545452