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Merck
CN

H9003

Hydroquinone

ReagentPlus®, ≥99%

Synonym(s):

1,4-Benzenediol, 1,4-Dihydroxybenzene, HQ

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About This Item

Linear Formula:
C6H4-1,4-(OH)2
CAS Number:
Molecular Weight:
110.11
UNSPSC Code:
12352005
NACRES:
NA.77
PubChem Substance ID:
EC Number:
204-617-8
Beilstein/REAXYS Number:
605970
MDL number:
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biological source

synthetic

Quality Level

vapor density

3.81 (vs air)

vapor pressure

1 mmHg ( 132 °C)

product line

ReagentPlus®

assay

≥99%

form

powder

autoignition temp.

930 °F

bp

285 °C (lit.)

mp

172-175 °C (lit.)

solubility

water: 50 mg/mL, clear

SMILES string

Oc1ccc(O)cc1

InChI

1S/C6H6O2/c7-5-1-2-6(8)4-3-5/h1-4,7-8H

InChI key

QIGBRXMKCJKVMJ-UHFFFAOYSA-N

General description

Hydroquinone is a phenolic compound, which is naturally found in coffee, tea and wine. It is used in photographic, chemical and cosmetic industries. Hydroquinone is used as a skin lightening agent. It is topically applied to treat melisma, freckles and senile lentigines. Hydroquinone is linked to exogenous ochronosis, dermatitis and skin irritation. It inhibits melanogenesis.

Application

Hydroquinone has been used as reagent for the conversion of DNA by sodium bisulfite. It has also been used as a chemical in Timm′s staining.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany


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Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Dam. 1 - Muta. 2 - Skin Sens. 1B

Storage Class

11 - Combustible Solids

flash_point_f

329.0 °F - closed cup

flash_point_c

165 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

危险化学品

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Topical use of hydroquinone as a depigmenting agent
Arndt KA and Fitzpatrick TB
JAMA : The Journal of the American Medical Association, 194(9), 965-967 (1965)
Increased frequency of CpG island methylator phenotype and CDH1 methylation in a gastric cancer high-risk region of china
Zhang KL, et al.
Translational Oncology, 1(1), 28-35 (2008)
Procedures in Cosmetic Dermatology Series: Cosmeceuticals E-Book (2008)



Global Trade Item Number

SKUGTIN
H9003-100G04061835545643
H9003-1KG04061835545650
H9003-500G04061835545667