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Merck
CN

H9026

Sodium hexanesulfonate

BioXtra

Synonym(s):

1-Hexanesulfonic acid sodium salt

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About This Item

Linear Formula:
C6H13O3SNa
CAS Number:
Molecular Weight:
188.22
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12161900
EC Number:
220-601-3
MDL number:
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description

anionic

Quality Level

product line

BioXtra

form

solid

mol wt

188.22 g/mol

technique(s)

HPLC: suitable

impurities

<0.001% Phosphorus (P), <0.1% Insoluble matter

solubility

H2O: 0.1 M at 20 °C, clear, colorless

cation traces

Al: <0.0005%, Ca: <0.0005%, Cu: <0.0005%, Fe: <0.0005%, K: <0.005%, Mg: <0.0005%, NH4+: <0.05%, Pb: <0.001%, Zn: <0.0005%

application(s)

(Ion Pair chromatography)

SMILES string

[Na+].CCCCCCS([O-])(=O)=O

InChI

1S/C6H14O3S.Na/c1-2-3-4-5-6-10(7,8)9;/h2-6H2,1H3,(H,7,8,9);/q;+1/p-1

InChI key

QWSZRRAAFHGKCH-UHFFFAOYSA-M

Application

<ul>
<li><strong>Ion pair assisted micro matrix solid phase dispersion extraction of alkaloids from medical plant</strong>: Sodium hexanesulfonate was used as an ion-pairing reagent in the extraction of alkaloids for pharmacological studies, demonstrating its efficacy in enhancing the selectivity and sensitivity of HPLC methods in the analysis of complex plant matrices (Dong et al., 2020).</li>
<li><strong>Pharmacokinetic Properties of Arsenic Species after Intravenous and Intragastrical Administration of Arsenic Trioxide Solution in Cynomolgus Macaques Using HPLC-ICP-MS</strong>: This study highlights the role of Sodium hexanesulfonate in improving the chromatographic profiles of arsenic species, which is crucial for accurate pharmacokinetic assessment in pharmaceutical research (Shi et al., 2019).</li>
<li><strong>Organic solvent-free reversed-phase ion-pairing liquid chromatography coupled to atomic fluorescence spectrometry for organoarsenic species determination in several matrices</strong>: Sodium hexanesulfonate is utilized as a solvent-free ion-pairing agent, enabling greener analytical processes without compromising the performance of liquid chromatography systems (Monasterio et al., 2011).</li>
</ul>


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Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Kirti S Niralwad et al.
Ultrasonics sonochemistry, 17(5), 760-763 (2010-03-17)
1-Hexanesulphonic acid sodium salt was found to be an efficient catalyst for the green synthesis of alpha-aminophosphonates by the coupling of aldehydes/ketone, an amine and triethyl phosphite under ultrasound irradiation at ambient temperature for appropriate time to furnish the desired
Philip Zakaria et al.
Electrophoresis, 23(17), 2821-2832 (2002-09-11)
The separation of a series of aromatic carboxylic acids, sulfonates and opiates using electrokinetic chromatography employing a mixture of the soluble cationic polymer poly(diallydimethylammonium chloride) (PDDAC) and the amphiphilic anion hexanesulfonate as pseudostationary phases is described. In this system, the
A R Calhoun et al.
Journal of colloid and interface science, 309(2), 505-510 (2007-03-03)
Measurements have been made to determine the solubility of ethane, C2H6, in aqueous solutions of four different surfactants of the linear alkanesulfonate class at 25 degrees C. The surfactants, sodium 1-pentanesulfonate, sodium 1-hexanesulfonate, sodium 1-heptanesulfonate, and sodium 1-octanesulfonate, all share



Global Trade Item Number

SKUGTIN
H9026-5G04061833811863
H9026-25G04061835545674