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M2649

Melanin from Sepia officinalis

99% purity (TLC), powder

Synonym(s):

Melanin

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About This Item

CAS Number:
UNSPSC Code:
12171500
NACRES:
NA.47
EC Number:
232-473-6
MDL number:
Technical Service
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Product Name

Melanin from Sepia officinalis, 99% (TLC)

Quality Level

assay

99% (TLC)

form

powder

solubility

hydrogen peroxide: 1 mg/mL, dark brown

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

SMILES string

[nH]1c2c3c(c4c5c([nH]c4)c([c]([c](c5c3c1)=O)=O)C)[c]([c](c2C)=O)=O

InChI

1S/C18H10N2O4/c1-5-13-9-7(3-19-13)12-10-8(11(9)17(23)15(5)21)4-20-14(10)6(2)16(22)18(12)24/h3-4,19-20H,1-2H3

InChI key

XUMBMVFBXHLACL-UHFFFAOYSA-N

General description

Melanin is a ubiquitous and prominent pigment responsible for color of skin, hair and eyes. Melanin is classified into eumelanin and pheomelanin. Eumelanin is black to dark brown pigment and is present in black hair and retina of the eye. Pheomelanin is yellow to reddish brown pigment present is red hair and red feathers. Melanins are high molecular weight pigments synthesized from phenolic or indolic precursors and is widely present in animals, plants and microorganisms.

Application

Melanin from Sepia officinalis has been used:
  • as a natural pigment for Raman spectroscopy measurements
  • in competitive enzyme linked immunosorbent assay (ELISA) for the characterization of phage antibodies
  • as an external standard for spectrophotometrically determining the melanin production in B16F10 cells

Biochem/physiol Actions

Melanin scavenges active chemical species and acts as a sunscreen.


Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Bor-Kai Hsiung et al.
The Journal of experimental biology, 218(Pt 22), 3632-3635 (2015-10-10)
Melanin pigments are broadly distributed in nature - from bacteria to fungi to plants and animals. However, many previous attempts to identify melanins in spiders were unsuccessful, suggesting that these otherwise ubiquitous pigments were lost during spider evolution. Yet, spiders
Optical properties of melanin in the skin and skinlike phantoms.
Bashkatov AN
SPIE Proc. (2000)
Sunil Kalia et al.
Pigment cell & melanoma research, 31(1), 31-38 (2017-08-15)
Objective measurements of melanin can provide important information for differentiating melanoma from benign pigmented lesions and in assessing pigmentary diseases. Herein, we evaluate near-infrared (NIR) fluorescence as a possible tool to quantify melanin. Various concentrations of in vitro Sepia melanin



Global Trade Item Number

SKUGTIN
M2649-100MG04061832343488
M2649-1G04061834045892