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O0270000

Oxybuprocaine hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Benoxinate hydrochloride, 2-(Diethylamino)ethyl 4-amino-3-butoxybenzoate hydrochloride, 4-Amino-3-butoxybenzoic acid diethylaminoethyl ester, Oxybuprocaine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C17H28N2O3 · HCl
CAS Number:
5987-82-6
Molecular Weight:
344.88
NACRES:
NA.24
PubChem Substance ID:
329818835
UNSPSC Code:
41116107
MDL number:
MFCD00012512
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grade

pharmaceutical primary standard

API family

oxybuprocaine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Cl[H].CCCCOc1cc(ccc1N)C(=O)OCCN(CC)CC

InChI

1S/C17H28N2O3.ClH/c1-4-7-11-21-16-13-14(8-9-15(16)18)17(20)22-12-10-19(5-2)6-3;/h8-9,13H,4-7,10-12,18H2,1-3H3;1H

InChI key

PRGUDWLMFLCODA-UHFFFAOYSA-N

Gene Information

human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Oxybuprocaine hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Cirous Dehghani et al.
Investigative ophthalmology & visual science, 55(5), 3195-3199 (2014-04-26)
We examined the age-dependent alterations and longitudinal course of subbasal nerve plexus (SNP) morphology in healthy individuals. Laser-scanning corneal confocal microscopy, ocular screening, and health and metabolic assessment were performed on 64 healthy participants at baseline and at 12-month intervals
Leilei Zou et al.
Molecular vision, 20, 977-987 (2014-07-16)
Scleral remodeling is an important mechanism underlying the development of myopia. Atropine, an antagonist of G protein-coupled muscarinic receptors, is currently used as an off-label treatment for myopia. Regulator of G-protein signaling 2 (RGS2) functions as an intracellular selective inhibitor
Franziska Bucher et al.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 252(7), 1119-1126 (2014-05-31)
To analyze potential alterations in corneal nerve morphology and function in different stages of Fuchs' endothelial corneal dystrophy (FECD). Thirty eyes with FECD underwent in vivo confocal microscopy using the Heidelberg Retina Tomograph II (HRT II; Heidelberg Engineering, Heidelberg, Germany)
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Global Trade Item Number

SKUGTIN
O027000004061833813539