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P0250000

Pancuronium bromide

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

1,1′-[(2β,3α,5α,16β,17β)-3,17-bis(Acetyloxy)androstane-2,16-diyl]bis(1-methylpiperidinium) dibromide

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About This Item

Empirical Formula (Hill Notation):
C35H60Br2N2O4
CAS Number:
15500-66-0
Molecular Weight:
732.67
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329820026
MDL number:
MFCD00079223
Beilstein/REAXYS Number:
4226892
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grade

pharmaceutical primary standard

API family

pancuronium 

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

[Br-].[Br-].[H][C@@]12CC[C@]3([H])[C@]([H])(CC[C@]4(C)[C@@H](OC(C)=O)[C@H](C[C@@]34[H])[N+]5(C)CCCCC5)[C@@]1(C)C[C@@H]([C@H](C2)OC(C)=O)[N+]6(C)CCCCC6

InChI

1S/C35H60N2O4.2BrH/c1-24(38)40-32-21-26-13-14-27-28(35(26,4)23-31(32)37(6)19-11-8-12-20-37)15-16-34(3)29(27)22-30(33(34)41-25(2)39)36(5)17-9-7-10-18-36;;/h26-33H,7-23H2,1-6H3;2*1H/q+2;;/p-2/t26-,27+,28-,29-,30-,31-,32-,33-,34-,35-;;/m0../s1

InChI key

NPIJXCQZLFKBMV-YTGGZNJNSA-L

Gene Information

human ... CHRNA1(1134), CHRNB1(1140), CHRND(1144), CHRNE(1145), CHRNG(1146)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Pancuronium bromide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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M Bączyk et al.
The Journal of physiology, 592(19), 4313-4328 (2014-08-03)
The main aim of the present study was to examine to what extent long-lasting subcortical actions of transcranial direct current stimulation (tDCS) may be related to its presynaptic actions. This was investigated in the red nucleus, where tDCS was recently
M F Roizen et al.
Annals of internal medicine, 88(1), 64-68 (1978-01-01)
Pancuronium bromide is a nondepolarizing muscle relaxant approved to induce skeletal muscle relaxation during anesthesia and to facilitate the management of patients undergoing mechanical ventilation. The use of pancuronium bromide during surgery led to the appreciation that it has advantages
Pancuronium bromide: a review of its pharmacological properties and clinical application.
T M Speight et al.
Drugs, 4(3), 163-226 (1972-01-01)
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Global Trade Item Number

SKUGTIN
P025000004061833813607