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Merck
CN

P2126

L-Phenylalanine

≥98%

Synonym(s):

(S)-2-Amino-3-phenylpropionic acid

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About This Item

Linear Formula:
C6H5CH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
165.19
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-568-1
MDL number:
Beilstein/REAXYS Number:
1910408
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Product Name

L-Phenylalanine, reagent grade, ≥98%

grade

reagent grade

Quality Level

assay

≥98%

form

powder or crystals

color

white to off-white

mp

270-275 °C (dec.) (lit.)

solubility

1 M NH4OH: 50 mg/mL, clear, colorless

application(s)

detection

SMILES string

N[C@@H](Cc1ccccc1)C(O)=O

InChI

1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m0/s1

InChI key

COLNVLDHVKWLRT-QMMMGPOBSA-N

Gene Information

Application

L-Phenylalanine has been used in Fluo-4 Ca2+-assay in a study to demonstrate that G-protein coupled receptor 139 reference surrogate agonists 1a and 7c and L-phenylalanine share a common binding site. It has also been used to spike blood samples to study the effect of dried blood spots on newborn screening.

Biochem/physiol Actions

L-Phenylalanine is an essential aromatic amino acid. It has a role in metabolism as it forms a starting point for many pathways. This neutral amino acid is a precursor for tyrosine, epinephrine, dopamine and norepinephrine.


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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Effect of Dried Blood Spot Quality on Newborn Screening Analyte Concentrations and Recommendations for Minimum Acceptance Criteria for Sample Analysis
Roanna S. George, Stuart J. Moat
Clinical Chemistry (2016)
The GPR139 reference agonists 1a and 7c, and tryptophan and phenylalanine share a common binding site
Anne Cathrine
Scientific Reports (2017)
AMINO ACIDS | Metabolism
Encyclopedia of Food and Color Additives, 197-206 (2003)



Global Trade Item Number

SKUGTIN
P2126-500G04061834362548
P2126-100G04061835367412
P2126-1G-KC04061824071894
P2126-1KG04061835367429