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Merck
CN

P45907

Piperazine

99%, solid, suitable for synthesis, ReagentPlus®

Synonym(s):

1,4-Diazacyclohexane, Diethylenediamine

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About This Item

Empirical Formula (Hill Notation):
C4H10N2
CAS Number:
Molecular Weight:
86.14
NACRES:
NA.21
PubChem Substance ID:
eCl@ss:
39160301
UNSPSC Code:
12352100
EC Number:
203-808-3
MDL number:
Beilstein/REAXYS Number:
102555
Assay:
99%
Bp:
145-146 °C (lit.)
Vapor pressure:
0.8 mmHg ( 20 °C)
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Product Name

Piperazine, ReagentPlus®, 99%

vapor pressure

0.8 mmHg ( 20 °C)

Quality Level

product line

ReagentPlus®

assay

99%

form

solid

expl. lim.

14 %

dilution

(for general lab use)

impurities

<1% water

pH

10.8-11.8 (100 g/L)

bp

145-146 °C (lit.)

mp

109-112 °C (lit.)

solubility

H2O: 0.9 g/L at 20 °C

SMILES string

C1CNCCN1

InChI

1S/C4H10N2/c1-2-6-4-3-5-1/h5-6H,1-4H2

InChI key

GLUUGHFHXGJENI-UHFFFAOYSA-N

General description

Piperazine (PZ) is an amine solvent. The ability of aqueous PZ to absorb carbon dioxide (CO2) has been assessed. It is reported to cause paralysis in Ascaris worms. The analysis of the crystal structure of PZ at 150K shows the presence of layered structure with NH...N hydrogen-bonded chains.

Application

Piperazine may be used in the preparation of N-(hetero)arylpiperazines.
Intermediate for a wide range of pharmaceuticals, polymers, dyes, corrosion inhibitors, rubber accelerators and surfactants.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany


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Danger

Hazard Classifications

Eye Dam. 1 - Flam. Sol. 1 - Repr. 2 - Resp. Sens. 1B - Skin Corr. 1B - Skin Sens. 1B

Storage Class

4.1B - Flammable solid hazardous materials

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

危险化学品

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Absorption of carbon dioxide into aqueous piperazine: reaction kinetics, mass transfer and solubility.
Bishnoi S and Rochelle GT.
Chemical Engineering Science, 55(22), 5531-5543 (2000)
Investigations on the action of piperazine on Ascaris lumbricoides.
Norton S and De Beer EJ.
The American Journal of Tropical Medicine and Hygiene, 6(5), 898-905 (1957)
Synthesis of N-arylpiperazines from aryl halides and piperazine under a palladium tri-tert-butylphosphine catalyst.
Nishiyama M, et al.
Tetrahedron Letters, 39(7), 617-620 (1998)



Global Trade Item Number

SKUGTIN
P45907-100G04061835321377
P45907-12KG04061833694398
P45907-1KG04061834374862
P45907-500G04061834374886
P45907-5G04061834374893
P45907-2.5KG04061834374879