P5288
Polyvinylpyrrolidone
Molecular Biology, nucleic acid hybridization tested, mol wt 360,000
Synonym(s):
PVP, Polyvidone, Povidone
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About This Item
Linear Formula:
(C6H9NO)n
CAS Number:
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12161700
MDL number:
Quality Level
grade
Molecular Biology
form
powder
mol wt
360,000
suitability
nucleic acid hybridization tested
foreign activity
Endonuclease, exonuclease, RNase, none detected
SMILES string
C=CN1CCCC1=O
InChI
1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2
InChI key
WHNWPMSKXPGLAX-UHFFFAOYSA-N
General description
Polyvinylpyrrolidone is a large polymer containing a carbonyl, C-N and alkyl functional groups.
Application
Polyvinylpyrrolidone has been used:
- to perform intracytoplasmic sperm injection procedure
- in the preparation of endophyte coating agent mixture, to coat creeping bentgrass seed
- as a component of prehybridization solution
Biochem/physiol Actions
Polyvinylpyrrolidone can bind to polyphenol. Thus, it is known to be used for RNA isolation from plants rich in polyphenols. It is extensively used in the synthesis of nanoparticles.
Other Notes
Polyvinylpyrrolidone is a component of Denhardt′s Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution.
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Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Inclusion of polyvinylpyrrolidone in the polymerase chain reaction reverses the inhibitory effects of polyphenolic contamination of RNA
Koonjul PK, et al.
Nucleic Acids Research, 27(3), 915-916 (1999)
Relevance of in vitro agar based screens to characterize the anti-fungal activities of bacterial endophyte communities
Shehata HR, et al.
BMC Microbiology, 16(1), 8-8 (2016)
Jan Konietzka et al.
Current biology : CB, 30(1), 1-16 (2019-12-17)
Sleep requires sleep-active neurons that depolarize to inhibit wake circuits. Sleep-active neurons are under the control of homeostatic mechanisms that determine sleep need. However, little is known about the molecular and circuit mechanisms that translate sleep need into the depolarization
Global Trade Item Number
| SKU | GTIN |
|---|---|
| P5288-500G | 04061834378136 |
| P5288-100G | 04061834377542 |
| P5288-1KG | 04061834378099 |