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Merck
CN

P6474

TWEEN® 80

viscous liquid, Preservative Free, Low-peroxide; Low-carbonyls

Synonym(s):

Tween® 80KR, POE (20) sorbitan monooleate, Polyethylene glycol sorbitan monooleate, Polyoxyethylenesorbitan monooleate, Polysorbate 80

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About This Item

CAS Number:
UNSPSC Code:
12161900
NACRES:
NA.21
MDL number:
Technical Service
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Quality Level

description

non-ionic

form

viscous liquid

mol wt

micellar avg mol wt 79,000

composition

Oleic acid, ~70% (balance primarily linoleic, palmitic, and stearic acids)

aggregation number

60

impurities

≤0.5 μmol/g Peroxides, ≤1.0 μmol/g Carbonyls, ≤3.0% water

CMC

0.012 mM (20-25°C)

transition temp

cloud point 65 °C

density

1.06 g/mL at 25 °C

HLB

15

storage temp.

−20°C

SMILES string

CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(C1C(CC(O1)OCCO)OCCO)OCCO

InChI

1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-27-29(39-22-19-34)32-28(38-21-18-33)26-31(42-32)41-23-20-35/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+

InChI key

RGPBUVUVZKQNHD-MDZDMXLPSA-N

Application

Non-ionic detergent used for selective protein extraction and isolation of nuclei from mammalian cell lines.

Legal Information

TWEEN is a registered trademark of Croda International PLC


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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

>235.4 °F - closed cup

flash_point_c

> 113 °C - closed cup

ppe

Eyeshields, Gloves



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Stephanie J Alexopoulos et al.
Nature communications, 11(1), 2397-2397 (2020-05-16)
Obesity is a health problem affecting more than 40% of US adults and 13% of the global population. Anti-obesity treatments including diet, exercise, surgery and pharmacotherapies have so far failed to reverse obesity incidence. Herein, we target obesity with a
Martin L Cross et al.
Clinical and vaccine immunology : CVI, 16(9), 1378-1380 (2009-07-03)
Cultures of Mycobacterium bovis BCG, comprising predominantly single-cell bacilli, were prepared in broth without animal-derived reagents. When formulated into a vegetable-derived lipid matrix, the vaccine was stable in vitro and was immunogenic in vivo upon feeding it to mice. This
Syed A Sattar et al.
PloS one, 6(2), e17340-e17340 (2011-03-11)
Human noroviruses (HuNoV), a major cause of acute gastroenteritis worldwide, cannot be readily cultured in the lab. Therefore, a feline calicivirus (FCV) is often used as its surrogate to, among other things, test alcohol-based handrubs (ABHR). The more recent laboratory



Global Trade Item Number

SKUGTIN
P6474-10ML04061834393450
P6474-100ML04061834393443
P6474-5X10ML04061834393467