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PHR1054

Riboflavin

Name: Riboflavin
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

(−)-Riboflavin, Lactoflavin, Vitamin B₂, Vitamin G

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About This Item

Empirical Formula (Hill Notation):

C₁₇H₂₀N₄O₆

CAS Number:

83-88-5

Molecular Weight:

376.36

NACRES:

NA.24

PubChem Substance ID:

329823084

eCl@ss:

34058005

UNSPSC Code:

41116107

EC Number:

201-507-1

MDL number:

MFCD00005022

Beilstein/REAXYS Number:

97825

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Properties

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. R060000, traceable to USP 1603006

API family

riboflavin

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

290 °C (dec.) (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC1=C(C)C=C(N(C[C@H](O)[C@@H]([C@H](O)CO)O)C(C2=N3)=NC(NC2=O)=O)C3=C1

InChI

1S/C17H20N4O6/c1-7-3-9-10(4-8(7)2)21(5-11(23)14(25)12(24)6-22)15-13(18-9)16(26)20-17(27)19-15/h3-4,11-12,14,22-25H,5-6H2,1-2H3,(H,20,26,27)/t11-,12+,14-/m0/s1

InChI key

AUNGANRZJHBGPY-SCRDCRAPSA-N

Description

General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards.

Application

Riboflavin may also be used as a reference standard for the determination of the analyte in cooked sausages and energy drinks by various chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAC0268 in the slot below. This is an example certificate only and may not be the lot that you receive.

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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

Determination of vitamins B and preservatives

Learn to separate and quantify B vitamins and preservatives in capsules with HPLC-UV and Purospher^® STAR RP-8 column. Validated for precision.

Determination of total riboflavin in cooked sausages

Valls F, et al.

Journal of Agricultural and Food Chemistry, 47(3), 1067-1070 (1999)

Rapid method for determination of riboflavin in urine by high-performance liquid chromatography

Smith DM, et al.

Journal of Chromatography. B, Biomedical Sciences and Applications, 182(3), 285-291 (1980)

Simultaneous determination of riboflavin, pyridoxine, nicotinamide, caffeine and taurine in energy drinks by planar chromatography-multiple detection with confirmation by electrospray ionization mass spectrometry

Aranda M and Morlock G

Journal of Chromatography A, 1131(1-2), 253-260 (2006)

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Global Trade Item Number

SKU	GTIN
PHR1054-1G	04061835237197