PHR1075
Cimetidine
Pharmaceutical Secondary Standard; Certified Reference Material
Synonym(s):
SKF-92334
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About This Item
Empirical Formula (Hill Notation):
C10H16N6S
CAS Number:
Molecular Weight:
252.34
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
257-232-2
MDL number:
Quality Level
grade
certified reference material, pharmaceutical secondary standard
agency
traceable to Ph. Eur. C2175000, traceable to USP 1134062
API family
cimetidine
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
CN\C(NC#N)=N\CCSCc1nc[nH]c1C
InChI
1S/C10H16N6S/c1-8-9(16-7-15-8)5-17-4-3-13-10(12-2)14-6-11/h7H,3-5H2,1-2H3,(H,15,16)(H2,12,13,14)
InChI key
AQIXAKUUQRKLND-UHFFFAOYSA-N
Gene Information
human ... HRH2(3274)
General description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Cimetidine is an H2 receptor antagonist drug. It can inhibit the photosensitive response on the skin typically induced by most of the fluoroquinolones.
Cimetidine is an H2 receptor antagonist drug. It can inhibit the photosensitive response on the skin typically induced by most of the fluoroquinolones.
Application
Cimetidine may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Analysis Note
These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA7170 in the slot below. This is an example certificate only and may not be the lot that you receive.
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Storage Class
11 - Combustible Solids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Simultaneous determination of moxifloxacin and H2 receptor antagonist in pharmaceutical dosage formulations by RP-HPLC: application to in vitro drug interactions
Sultana N, et al.
Quimica nova, 34(4), 683-688 (2011)
Y Edrei et al.
British journal of cancer, 107(4), 658-666 (2012-07-19)
The poor prognosis of patients with colorectal-cancer liver metastases (CRLM) and the insufficiency of available treatments have raised the need for alternative curative strategies. We aimed to assess the therapeutic potential of TL-118, a new anti-angiogenic drug combination, for CRLM
J E Naschitz et al.
Seminars in arthritis and rheumatism, 21(4), 211-220 (1992-02-01)
The term fasciitis-panniculitis syndrome (FPS) is proposed as a novel compilation encompassing several disorders, common to which is subcutaneous induration caused by cicatrizing fasciitis as well as septal and lobular panniculitis and perimysial fibrosis. Included herein are Shulman's eosinophilic fasciitis
Global Trade Item Number
| SKU | GTIN |
|---|---|
| PHR1075-1G | 04061834413417 |