PHR1103
L-Serine
Pharmaceutical Secondary Standard; Certified Reference Material
Synonym(s):
(S)-2-Amino-3-hydroxypropionic acid
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About This Item
Linear Formula:
HOCH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
105.09
NACRES:
NA.24
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
41116107
EC Number:
200-274-3
MDL number:
Beilstein/REAXYS Number:
1721404
Quality Level
grade
certified reference material, pharmaceutical secondary standard
agency
traceable to Ph. Eur. S0450000, traceable to USP 1612506
API family
serine
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
mp
222 °C (dec.) (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
SMILES string
N[C@@H](CO)C(O)=O
InChI
1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1
InChI key
MTCFGRXMJLQNBG-REOHCLBHSA-N
General description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Application
L-Serine may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by ion chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Biochem/physiol Actions
Precursor of glycine by serine hydroxymethyltransferase.
Analysis Note
These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA7166 in the slot below. This is an example certificate only and may not be the lot that you receive.
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Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Ion-chromatographic determination of carbocisteine in pharmaceuticals based on non-suppressed conductimetric detection
Megoulas NC and Koupparis MA
Journal of Chromatography A, 1026(1-2), 167-174 (2004)
Cedric Cagliero et al.
Nucleic acids research, 41(12), 6058-6071 (2013-05-02)
To fit within the confines of the cell, bacterial chromosomes are highly condensed into a structure called the nucleoid. Despite the high degree of compaction in the nucleoid, the genome remains accessible to essential biological processes, such as replication and
Hisaaki Shinohara et al.
Science (New York, N.Y.), 344(6185), 760-764 (2014-05-17)
A switchlike response in nuclear factor-κB (NF-κB) activity implies the existence of a threshold in the NF-κB signaling module. We show that the CARD-containing MAGUK protein 1 (CARMA1, also called CARD11)-TAK1 (MAP3K7)-inhibitor of NF-κB (IκB) kinase-β (IKKβ) module is a
Global Trade Item Number
| SKU | GTIN |
|---|---|
| PHR1103-1G | 04061835233007 |