Skip to Content
Merck
CN

Key Documents

View All Documentation

PHR1210

Cumene

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

(1-Methylethyl)benzene, 2-Phenylpropane, Isopropylbenzene, NSC 8776

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Linear Formula:
C6H5CH(CH3)2
CAS Number:
98-82-8
Molecular Weight:
120.19
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329823217
EC Number:
202-704-5
Beilstein/REAXYS Number:
1236613
MDL number:
MFCD00008881
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1151709

vapor density

4.1 (vs air)

vapor pressure

8 mmHg ( 20 °C), 9.7 mmHg ( 37.7 °C)

API family

cumene

CofA

current certificate can be downloaded

autoignition temp.

797 °F

expl. lim.

6.5 %

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

refractive index

n20/D 1.491 (lit.)

bp

152-154 °C (lit.)

mp

−96 °C (lit.)

density

0.864 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

CC(C)c1ccccc1

InChI

1S/C9H12/c1-8(2)9-6-4-3-5-7-9/h3-8H,1-2H3

InChI key

RWGFKTVRMDUZSP-UHFFFAOYSA-N

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Cumene may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA9023 in the slot below. This is an example certificate only and may not be the lot that you receive.

Still not finding the right product?

Explore all of our products under Cumene

signalword

Danger

Hazard Classifications

Aquatic Chronic 2 - Asp. Tox. 1 - Carc. 1B - Flam. Liq. 3 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

87.8 °F - closed cup

flash_point_c

31.0 °C - closed cup

Regulatory Information

危险化学品

This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Determination of Residual Solvents in Bulk Drug and Formulations
Singh P and Sinha M
American Journal of PharmTech Research, 3(4), 289-295 (2006)
A novel peroxy radical based oxidative stressing system for ranking the oxidizability of drug substances
Harmon PA. et al.
Journal of Pharmaceutical Sciences, 95(9), 2014-2028 (2006)
Mathieu Frenette et al.
Journal of the American Chemical Society, 128(51), 16432-16433 (2006-12-21)
A new class of thermally activated chain-breaking antioxidants is presented. Dimers of persistent carbon-centered radicals are able to inhibit the autoxidation of cumene and styrene with better rate constants than the commercial antioxidant Irganox HP-136 and 3,5-di-tert-butyl-4-hydroxyanisole. A dramatic increase
View All Related Papers

Global Trade Item Number

SKUGTIN
PHR1210-3X1.2ML04061837884009