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PHR1215

Lactic acid

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

DL-Lactic acid, 2-Hydroxypropionic acid

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About This Item

Linear Formula:
CH3CH(OH)COOH
CAS Number:
50-21-5
Molecular Weight:
90.08
NACRES:
NA.24
E Number:
E270
PubChem Substance ID:
329823222
UNSPSC Code:
41116107
EC Number:
200-018-0
MDL number:
MFCD00004520
Beilstein/REAXYS Number:
1209341
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Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1356734

API family

lactic acid

form

liquid

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

refractive index

n20/D 1.425 (lit.)

bp

122 °C/15 mmHg (lit.)

density

1.209 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

storage temp.

2-8°C

SMILES string

CC(O)C(O)=O

InChI

1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)

InChI key

JVTAAEKCZFNVCJ-UHFFFAOYSA-N

General description

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

This pharmaceutical secondary standard can also be used as follows:

  • Quantitative analysis of four short-chain fatty acids and lactic acids by high-performance liquid chromatography (HPLC) combined with a UV detector from the supernatant of bacterial cultures
  • Spectrophotometric determination of lactic acid at 390 nm in biological cultural and dairy products

Analysis Note

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
To see an example of a Certificate of Analysis for this material enter LRAC0299 in the slot below. This is an example certificate only and may not be the lot that you receive.

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pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1C

supp_hazards

EUH071

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 1

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Protocols

HPLC Analysis of Lactic Acid Enantiomers on Astec CLC-L, Trace Level Detection

Separation of DL-Lactic acid, ~90% (T)

HPLC Analysis of Organic Acids in Wine/Beer on TSKgel®

Science Slam panel: Leading gene therapy developers discuss commercialization challenges and the importance of robust process development plans.

Articles

Separation of Organic Acids with 100% aqueous mobile phase using an Ascentis® Express AQ-C18 HPLC Column

A new RP-HPLC method is proposed for the determination of organic acids in 100% aqueous mobile phase using an Ascentis® Express AQ-C18 column

Paula Gaspar et al.
Biotechnology advances, 31(6), 764-788 (2013-04-10)
The lactic acid bacteria (LAB) are a functionally related group of low-GC Gram-positive bacteria known essentially for their roles in bioprocessing of foods and animal feeds. Due to extensive industrial use and enormous economical value, LAB have been intensively studied
Eileen F O' Shea et al.
Current opinion in biotechnology, 24(2), 130-134 (2013-01-23)
Lactic acid bacteria (LAB) produce a wide variety of antimicrobial peptides (bacteriocins) which contribute to the safety and preservation of fermented foods. This review discusses strategies that have been or could be employed to further enhance the commercial application of
Jan Martinussen et al.
Current opinion in biotechnology, 24(2), 124-129 (2012-12-26)
The ability of lactic acid bacteria to produce lactic acid from various sugars plays an important role in food fermentations. Lactic acid is derived from pyruvate, the end product of glycolysis and thus a fast lactic acid production rate requires
View All Related Papers

Global Trade Item Number

SKUGTIN
PHR1215-3X1.5ML04061834414629