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PHR1560

tert-Butyl Methyl Ether

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

tert-Butyl methyl ether, MTBE, Methyl tert-butyl ether

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About This Item

Linear Formula:
(CH3)3COCH3
CAS Number:
Molecular Weight:
88.15
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
216-653-1
Beilstein/REAXYS Number:
1730942
MDL number:
Technical Service
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Quality Level

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1083303

vapor density

3.1 (vs air)

CofA

current certificate can be downloaded

autoignition temp.

705 °F

expl. lim.

15.1 %

packaging

ampule of 3x1.2 mL

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

refractive index

n20/D 1.369 (lit.)

bp

55-56 °C (lit.)

density

0.74 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

COC(C)(C)C

InChI

1S/C5H12O/c1-5(2,3)6-4/h1-4H3

InChI key

BZLVMXJERCGZMT-UHFFFAOYSA-N

General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. tert-Butyl methyl ether (MTBE) is a gasoline additive. It is a commonly used organic solvent that can be synthesized by acid catalyzed reaction between methanol and isobutene. It is also an effective alternative to lead containing additives for enhancing the octane rating of gasoline.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC2091 in the slot below. This is an example certificate only and may not be the lot that you receive.


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pictograms

FlameExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Flam. Liq. 2 - Skin Irrit. 2

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

-18.4 °F - closed cup

flash_point_c

-28 °C - closed cup

Regulatory Information

危险化学品

This item has



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ceinwen A Schreiner et al.
Regulatory toxicology and pharmacology : RTP, 70(2 Suppl), S29-S34 (2014-05-24)
Micronucleus and sister chromatid exchange (SCE) tests were performed for vapor condensate of baseline gasoline (BGVC), or gasoline with oxygenates, methyl tert-butyl ether (G/MTBE), ethyl tert butyl ether (G/ETBE), t-amyl methyl ether (G/TAME), diisopropyl ether (G/DIPE), t-butyl alcohol (TBA), or
Yi-Hsueh Chuang et al.
Journal of hazardous materials, 283, 218-226 (2014-10-04)
During the chloramination of natural waters, both chloramines and dissolved organic nitrogen (DON) can serve as nitrogen sources for the formation of trichloronitromethane (TCNM) and dichloroacetonitrile (DCAN). The present study investigated the formation kinetics and precursor characteristics of TCNM and
Shilo Rosenwasser et al.
The Plant cell, 26(6), 2689-2707 (2014-06-13)
Marine viruses are major ecological and evolutionary drivers of microbial food webs regulating the fate of carbon in the ocean. We combined transcriptomic and metabolomic analyses to explore the cellular pathways mediating the interaction between the bloom-forming coccolithophore Emiliania huxleyi



Global Trade Item Number

SKUGTIN
PHR1560-3X1.2ML04061837884177