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S2000000

Sulfamerazine

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

4-Amino-N-(4-methyl-2-pyrimidinyl)benzenesulfonamide, N1-(4-Methylpyrimidin-2-yl)sulfanilamide

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About This Item

Empirical Formula (Hill Notation):
C11H12N4O2S
CAS Number:
127-79-7
Molecular Weight:
264.30
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329824501
MDL number:
MFCD00023212
Beilstein/REAXYS Number:
249133
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grade

pharmaceutical primary standard

API family

sulfamerazine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Cc1ccnc(NS(=O)(=O)c2ccc(N)cc2)n1

InChI

1S/C11H12N4O2S/c1-8-6-7-13-11(14-8)15-18(16,17)10-4-2-9(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15)

InChI key

QPPBRPIAZZHUNT-UHFFFAOYSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Sulfamerazine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Pól Macfhionnghaile et al.
Journal of pharmaceutical sciences, 103(6), 1766-1778 (2014-04-24)
The effects of ball-milling and cryomilling on sulfamerazine forms I and II (SMZ FI, FII) were investigated using X-ray powder diffraction, infrared and near-infrared (NIR) spectroscopy. Cryomilling resulted in a complete amorphization of both polymorphs. Milling at room temperature gave
Zhe Meng et al.
Food chemistry, 174, 597-605 (2014-12-23)
A novel UPLC-MS/MS method for quantification and confirmation of eight fluoroquinolones, five sulphonamides (SAs) and four acetyled metabolites in milk is developed. Their main fragmentation pathways were presented. The limits of quantification were in the range of 0.01-0.29 μg kg(-1)
Qing Wang et al.
Analytica chimica acta, 854, 191-201 (2014-12-07)
A hydrophilic stationary phase (SP) was prepared through grafting N-methylene phosphonic acid chitosan on magnesia-zirconia particles (P-CTS-MgO-ZrO2) via Lewis acid-base interaction. The resulting material was characterized by thermogravimetric analysis, Fourier transform infrared spectroscopy, scanning electron microscope and nitrogen adsorption analysis.
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Global Trade Item Number

SKUGTIN
S200000004061833815168