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T4562

Thiamine hydrochloride

meets USP testing specifications

Synonym(s):

Aneurine hydrochloride, Vitamin B1 hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C12H17ClN4OS · HCl
CAS Number:
67-03-8
Molecular Weight:
337.27
NACRES:
NA.21
PubChem Substance ID:
24900215
eCl@ss:
34058006
UNSPSC Code:
12352116
EC Number:
200-641-8
MDL number:
MFCD00012780
Beilstein/REAXYS Number:
3851771
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biological source

synthetic (organic)

Quality Level

200

agency

USP/NF, meets USP testing specifications

assay

98.0-102.0%

form

solid

mp

250 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

SMILES string

CC1=NC(N)=C(C[N+]2=CSC(CCO)=C2C)C=N1.Cl.[Cl-]

InChI

1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1

InChI key

DPJRMOMPQZCRJU-UHFFFAOYSA-M

Application

Required to support energy metabolism and amino acid synthesis in cultured cells. Present in many classical and serum-free formulations.

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
SLCK7986
SLCH7916
SLCF6098
SLBV0751
041M0041V

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Articles

Thiamine in Cell Culture

Explore thiamine's impact on serum-free cell culture systems for biomanufacturing monoclonal antibodies.

Joseph E Kerschner et al.
Archives of otolaryngology--head & neck surgery, 135(1), 33-39 (2009-01-21)
To investigate genetic differences in middle ear mucosa (MEM) with nontypeable Haemophilus influenzae (NTHi) infection. Genetic upregulation and downregulation occurs in MEM during otitis media (OM) pathogenesis. A comprehensive assessment of these genetic differences using the techniques of complementary DNA
Samir Ahmed El-Shazly et al.
International journal of immunopathology and pharmacology, 28(2), 227-239 (2015-03-31)
Diabetes mellitus (DM) is a chronic metabolic disorder characterized by hyperglycemia due to abnormalities in either insulin secretion or action. A range of vanadium complexes have been synthesized and demonstrated to be effective in lowering hyperglycemia. Thiamine administration was also
Ashish K Singh et al.
Alcoholism, clinical and experimental research, 38(7), 2127-2137 (2014-06-17)
Chronic ethanol (EtOH) consumption is associated with oxidative tissue damage, decrease in antioxidant enzyme activities, and increase in hepatic and plasma lipids. This study investigates the effect of modified probiotic Escherichia coli Nissle 1917 (EcN) secreting pyrroloquinoline quinone (PQQ) against
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Global Trade Item Number

SKUGTIN
T4562-25G04061835550036
T4562-1KG04061835535873
T4562-250G04061833624791