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Merck
CN

T7875

Thiourea

≥99.0%, ReagentPlus®

Synonym(s):

Sulfourea, Thiocarbamide

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About This Item

Linear Formula:
NH2CSNH2
CAS Number:
Molecular Weight:
76.12
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
200-543-5
MDL number:
Beilstein/REAXYS Number:
605327
Assay:
≥99.0%
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Product Name

Thiourea, ReagentPlus®, ≥99.0%

Quality Level

product line

ReagentPlus®

assay

≥99.0%

mp

170-176 °C (lit.)

functional group

amine, thiourea

SMILES string

NC(N)=S

InChI

1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)

InChI key

UMGDCJDMYOKAJW-UHFFFAOYSA-N

Gene Information

mouse ... Ephx2(13850)

General description

Thiourea is an analogue of urea, containing sulphur.

Application

Thiourea has been used:
  • as a component in ice cold sample buffer for protein analysis
  • in intracellular extraction buffer for the extraction of soluble intracellular proteins
  • as a component of electrophoresis buffer

Chaotropic agent; strong denaturant. Increases solubility and recovery of proteins

Biochem/physiol Actions

Thiourea is a free radical scavenger of the peroxide radical. It was shown to inhibit lipid peroxidation and ultraviolet (UV)-induced crosslinking of collagen. Bud dormancy in plants can be inhibited by thiourea, which is used as a growth stimulator. It is also known to be used in the treatment of hyperthyroidism.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany


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Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Repr. 2

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

危险化学品

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Extraction of Intracellular and Cell Wall Proteins from Leaves and Roots of Harsh Hakea
Shane MW and Plaxton WC
Journal of Experimental Botany (2014)
Feline hypertrophic cardiomyopathy associated with the p. A31P Mutation in cMyBP-C is caused by production of mutated cMyBP-C with reduced binding to actin
Godiksen MTN, et al.
Open Journal of Veterinary Medicine, 3(02), 95-95 (2013)
Synergistic effects of glucose and ultraviolet irradiation on the physical properties of collagen
Ohan MP, et al.
Journal of Biomedical Materials Research, 60(3), 384-391 (2002)



Global Trade Item Number

SKUGTIN
T7875-12KG04061833644201
T7875-100G04061835322725
T7875-1KG04061835322732
T7875-500G04061835322749
T7875-5G04061835322756
T7875-5KG04061835322763