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Merck
CN

Y0000833

Clopamide

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

4-Chloro-N-(2,6-dimethylpiperidinyl)-3-sulfamoylbenzamide

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About This Item

Empirical Formula (Hill Notation):
C14H20ClN3O3S
CAS Number:
Molecular Weight:
345.84
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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grade

pharmaceutical primary standard

API family

clopamide

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

C[C@@H]1CCC[C@H](C)N1NC(=O)c2ccc(Cl)c(c2)S(N)(=O)=O

InChI

1S/C14H20ClN3O3S/c1-9-4-3-5-10(2)18(9)17-14(19)11-6-7-12(15)13(8-11)22(16,20)21/h6-10H,3-5H2,1-2H3,(H,17,19)(H2,16,20,21)/t9-,10+

InChI key

LBXHRAWDUMTPSE-AOOOYVTPSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Clopamide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.


pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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High-performance liquid chromatographic determination of xipamide and clopamide in pharmaceuticals.
Sane R T, et al.
Journal of Chromatography A, 356, 468-472 (1986)
Validated liquid chromatography?tandem mass spectrometry method for simultaneous determination of clopamide, reserpine and dihydroergotoxine: Application to pharmacokinetics in human plasma.
El-Din M M S, et al.
Journal of Pharmaceutical and Biomedical Analysis, 125, 236-244 (2016)
The Medical journal of Australia, 150(11), 646-646 (1989-06-05)
In an open study that was conducted in general practice, 22 patients with previously-untreated mild hypertension received an average daily dose of 11.7 mg of pindolol over a 50-week study period. The total cholesterol, high-density lipoprotein fraction and plasma triglyceride



Global Trade Item Number

SKUGTIN
Y000083304061833796597