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251755

Osmium tetroxide solution

4 wt. % in H2O

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About This Item

Linear Formula:
OsO4
CAS Number:
Molecular Weight:
254.23
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352303
MDL number:
Form:
liquid
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Quality Level

vapor pressure

1.23 psi ( 20 °C), 3.55 psi ( 55 °C)

form

liquid

reaction suitability

reagent type: oxidant

concentration

3.5-4.5% (OsO4), 4 wt. % in H2O

density

1.0 g/mL at 20 °C, 1.04 g/mL at 25 °C

storage temp.

2-8°C

SMILES string

O=[Os](=O)(=O)=O

InChI

1S/4O.Os

InChI key

VUVGYHUDAICLFK-UHFFFAOYSA-N

General description

OsO4 (4wt% in H2O) is widely employed in organic synthesis especially for hydroxylation reactions. Additionally, it is also involved in the oxidative cleavage of alkenes.

Application


  • In situ X-ray-assisted electron microscopy staining for large biological samples.: This study explores the use of osmium tetroxide solution for X-ray-assisted electron microscopy staining, enhancing the visualization of large biological samples (Ströh et al., 2022).

  • Application of the electron microscope to the cytochemical peroxidase reaction in salamander leukocytes.: The use of osmium tetroxide solution in electron microscopy enhances the cytochemical analysis of peroxidase reactions in salamander leukocytes, providing clear and detailed images (MITSUI, 1960).




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pictograms

Skull and crossbonesCorrosion

signalword

Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2

Storage Class

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

监管及禁止进口产品

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On stereochemistry of osmium tetroxide oxidation of allylic alcohol systems: empirical rule.
Cha JK, et al.
Tetrahedron Letters, 24(37), 3943-3946 (1983)
Kinetics of Oxidation of Some Fluoroquinolones by Hexacyanoferrate (III) in Alkaline Medium.
Diab N, et al.
International Journal of Chemistry (Canadian Center of Science and Education), 34(2), 1388-1388 (2013)
Asymmetric induction in the reaction of osmium tetroxide with olefins.
Hentges SG and Barry Sharpless K.
Journal of the American Chemical Society, 102(12), 4263-4265 (1980)



Global Trade Item Number

SKUGTIN
251755-10ML04061825937946
251755-2ML04061825937953
251755-5ML04061825937960