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34943

Dimethyl sulfoxide

Name: Dimethyl sulfoxide
Brand: SIGALD

puriss. p.a., dried, ≤0.02% water

Synonym(s):

DMSO

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About This Item

Linear Formula:

(CH₃)₂SO

CAS Number:

67-68-5

Molecular Weight:

78.13

UNSPSC Code:

12191502

NACRES:

NA.21

PubChem Substance ID:

329755094

EC Number:

200-664-3

Beilstein/REAXYS Number:

506008

MDL number:

MFCD00002089

Assay:

≥99.9% (GC)

Bp:

189 °C (lit.)

Vapor pressure:

0.42 mmHg ( 20 °C)

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Properties

vapor density

2.7 (vs air)

Quality Level

100

vapor pressure

0.42 mmHg ( 20 °C)

grade

puriss. p.a.

assay

≥99.9% (GC)

form

liquid

autoignition temp.

573 °F

quality

dried

expl. lim.

42 %, 63 °F

impurities

≤0.0001% heavy metals (as Pb), ≤0.001% free acid (as H₂SO₄), ≤0.002% non-volatile matter, ≤0.02% water, ≤0.03% water (Karl Fischer)

refractive index

n20/D 1.479 (lit.)

bp

189 °C (lit.)

mp

16-19 °C (lit.)

density

1.10 g/mL (lit.)

cation traces

Fe: ≤1 mg/kg

SMILES string

CS(C)=O

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

InChI key

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

Description

General description

Dimethyl sulfoxide (DMSO) is a polar solvent. DMSO activated by various electrophiles (oxalyl chloride) has been used to oxidize various alcohols (primary, secondary, allylic, benzylic, hindered and bicyclic). Carbonyl compounds are formed as reaction products. It has been proposed as an alternate solvent for methyl cellosolve for use in ninhydrin reaction, due to its high stability.

Application

Dimethyl sulfoxide (DMSO) has been used as a solvent in the high-throughput compound screening studies conducted on Mtb (Mycobacterium tuberculosis) H37Rv host cells.

Other Notes

For information on dimethyl sulfoxide miscibility, please visit the following link:
Dimethyl Sulfoxide Miscibility/Immiscibility Table

Disclaimer

Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

188.6 °F - closed cup

flash_point_c

87 °C - closed cup

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A microscopic phenotypic assay for the quantification of intracellular mycobacteria adapted for high-throughput/high-content screening.

Christophe J Queval et al.

Journal of visualized experiments : JoVE, (83)(83), e51114-e51114 (2014-01-30)

Despite the availability of therapy and vaccine, tuberculosis (TB) remains one of the most deadly and widespread bacterial infections in the world. Since several decades, the sudden burst of multi- and extensively-drug resistant strains is a serious threat for the

A RAPID PERMETHYLATION OF GLYCOLIPID, AND POLYSACCHARIDE CATALYZED BY METHYLSULFINYL CARBANION IN DIMETHYL SULFOXIDE.

S HAKOMORI

Journal of biochemistry, 55, 205-208 (1964-02-01)

Oxidation of alcohols by ?activated? dimethyl sulfoxide. A preparative, steric and mechanistic study.

Omura K and Swern D.

Tetrahedron, 34(11), 1651-1660 (1978)

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Global Trade Item Number

SKU	GTIN
34943-1L	04061837851179
34943-6X1L	04061837851216
34943P-4X2.5L	04061837851230