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Merck
CN

71650

Sodium phosphate dibasic dodecahydrate

puriss. p.a., crystallized, ≥99.0% (T)

Synonym(s):

sec-Sodium phosphate, Disodium hydrogen phosphate dodecahydrate, Disodium phosphate, di-Sodium hydrogen phosphate dodecahydrate

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About This Item

Linear Formula:
Na2HPO4 · 12H2O
CAS Number:
Molecular Weight:
358.14
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12161700
EC Number:
231-448-7
MDL number:
Assay:
≥99.0% (T)
Form:
crystals
Solubility:
water: soluble 35.8 g/L at 20 °C
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grade

puriss. p.a.

Quality Level

assay

≥99.0% (T)

form

crystals

quality

crystallized

pH

9.0-9.3 (25 °C, 50 mg/mL in H2O)

solubility

water: soluble 35.8 g/L at 20 °C

anion traces

chloride (Cl-): ≤5 mg/kg, fluoride (F-): ≤5 mg/kg, sulfate (SO42-): ≤50 mg/kg

cation traces

As: ≤0.5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

SMILES string

O.O.O.O.O.O.O.O.O.O.O.O.[Na+].[Na+].OP([O-])([O-])=O

InChI

1S/2Na.H3O4P.12H2O/c;;1-5(2,3)4;;;;;;;;;;;;/h;;(H3,1,2,3,4);12*1H2/q2*+1;;;;;;;;;;;;;/p-2

InChI key

DGLRDKLJZLEJCY-UHFFFAOYSA-L

General description

Sodium phosphate is a colorless crystalline sodium salt. It is widely used as a buffer in molecular biology, biochemistry, and chromatographic studies. It exists in three forms: monobasic (NaH2PO4), dibasic (Na2HPO4), and tribasic (Na3PO4). Monobasic and dibasic forms in varying ratios are commonly used to compose the neutral sodium phosphate buffer solution.

Application

Sodium phosphate dibasic dodecahydrate may be used to prepare the 0.1M phosphate buffer having pH 7.4.


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Storage Class

13 - Non Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable



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Chia Lin Chang et al.
Evidence-based complementary and alternative medicine : eCAM, 2012, 125247-125247 (2011-07-15)
The objectives of this study were to determine phytochemical compositions, chemiluminescence antioxidant activities, and neuroprotective effects on PC12 cells for water, methanol, and 95% ethanol extracts of the air-dried fruit of Terminalia chebula Retzius. The water extract afforded the greatest
Matthew H Crouthamel et al.
Arteriosclerosis, thrombosis, and vascular biology, 33(11), 2625-2632 (2013-08-24)
Elevated serum phosphate has emerged as a major risk factor for vascular calcification. The sodium-dependent phosphate cotransporter, PiT-1, was previously shown to be required for phosphate-induced osteogenic differentiation and calcification of cultured human vascular smooth muscle cells (VSMCs), but its
Matthew R Weir et al.
Journal of clinical hypertension (Greenwich, Conn.), 16(12), 875-882 (2014-10-21)
The effects of canagliflozin, a sodium glucose co-transporter 2 inhibitor, on blood pressure (BP) and osmotic diuresis- and intravascular volume reduction-related adverse events (AEs) were evaluated using pooled data from four placebo-controlled, phase 3 studies in patients with type 2



Global Trade Item Number

SKUGTIN
71650-1KG04061835563616