F7503
Formamide
ReagentPlus®, ≥99.0% (GC)
Synonym(s):
Amide C1, Formic amide
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About This Item
Linear Formula:
HCONH2
CAS Number:
Molecular Weight:
45.04
UNSPSC Code:
12352111
NACRES:
NA.21
PubChem Substance ID:
EC Number:
200-842-0
Beilstein/REAXYS Number:
505995
MDL number:
Assay:
≥99.0% (GC)
Technique(s):
hybridization: suitable
Bp:
210 °C (lit.)
Vapor pressure:
0.08 mmHg ( 20 °C), 30 mmHg ( 129 °C)
vapor density
1.55 (vs air)
Quality Level
vapor pressure
0.08 mmHg ( 20 °C), 30 mmHg ( 129 °C)
product line
ReagentPlus®
assay
≥99.0% (GC)
form
liquid
autoignition temp.
932 °F
expl. lim.
2.7-19 %
technique(s)
hybridization: suitable
refractive index
n20/D 1.447 (lit.)
pH
4-10 (20 °C, 200 g/L)
bp
210 °C (lit.)
mp
2-3 °C (lit.)
density
1.134 g/mL at 25 °C (lit.)
SMILES string
NC=O
InChI
1S/CH3NO/c2-1-3/h1H,(H2,2,3)
InChI key
ZHNUHDYFZUAESO-UHFFFAOYSA-N
General description
Formamide is a polar solvent mainly used for resins and plasticizers. It can be prepared by direct synthesis from carbon monoxide and ammonia.
Application
Formamide can be used as a solvent:
- To synthesize tetrakis(trialkylsilyl) diphosphate by reacting disodium dihydrogen diphosphate with trialkyl chlorosilane.
- In Cu/C catalyzed cycloaddition between azides and terminal alkynes to synthesize triazoles.
Formamide destabilizes nucleic acid duplexes and may be used, typically, at a concentration of 50%, in hybridization protocols requiring lower hybridization temperatures.
Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
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signalword
Danger
hcodes
Hazard Classifications
Carc. 2 - Repr. 1B - STOT RE 2 Oral
target_organs
Blood
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 1
flash_point_f
305.6 °F
flash_point_c
152 °C
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Related Content
Product Information Sheet
The crystal structure of formamide.
Ladell J and Post B.
Acta Crystallographica, 7(8-9), 559-564 (1954)
The formamide method for the extraction of polysaccharides from haemolytic streptococci.
Fuller AT.
British Journal of Experimental Pathology, 19(2), 130-130 (1938)
Microwave spectrum, structure, dipole moment, and quadrupole coupling constants of formamide.
Kurland RJ and Wilson Jr EB.
J. Chem. Phys., 27(2), 585-590 (1957)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| F7503-250ML | 04061833619643 |
| F7503-4L | 04061837227417 |
| F7503-100ML | 04061833619636 |
| F7503-1L | 04061837227387 |
| F7503-2.5L | 04061837227394 |
| F7503-500ML | 04061837227424 |