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Merck
CN

09963

(Hydroxypropyl)methyl cellulose

Synonym(s):

2-Hydroxypropyl methyl cellulose ether

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About This Item

CAS Number:
UNSPSC Code:
12352201
NACRES:
NA.25
MDL number:
Technical Service
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form

powder

Quality Level

composition

hydroxylpropoxyl content, ~9%

color

faint beige

viscosity

~15 mPa.s, 2 % in H2O(25 °C)

solubility

water: 100 mg/10 mL, clear, colorless

storage temp.

room temp

SMILES string

O3[C@H]([C@@H]([C@H]([C@@H]([C@H]3COCC(O)C)OCC(O)C)OCC(O)C)OCC(O)C)O[C@@H]4[C@H](O[C@H]([C@@H]([C@H]4OCC(O)C)OCC(O)C)OCC(O)C)COCC(O)C.O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1COC)OC)OC)OC)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2OC)OC)OC)COC

InChI

1S/C36H70O19.C20H38O11/c1-19(37)9-45-17-27-29(47-11-21(3)39)31(48-12-22(4)40)34(51-15-25(7)43)36(54-27)55-30-28(18-46-10-20(2)38)53-35(52-16-26(8)44)33(50-14-24(6)42)32(30)49-13-23(5)41;1-21-9-11-13(23-3)15(24-4)18(27-7)20(30-11)31-14-12(10-22-2)29-19(28-

InChI key

PUSNGFYSTWMJSK-GSZQVNRLSA-N

Application

Thickener for aqueous and non-aqueous systems, clear films with grease resistance, binders, lubricants, steric stabilizer and water retention aid.
(Hydroxypropyl)methyl cellulose (HPMC), an inert viscoelastic polymer is used as an emulsifier, thickening and suspending agent similar to animal gelatin. HPMC is used in the development of controlled-delivery medicament.

Features and Benefits

Dissolves in water, undergoes reversible gelation upon heating, non-ionic, does not complex with ionic species and is surface active and enzyme resistant. Solutions are pseudoplastic.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.


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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Punit P Shah et al.
Biomaterials, 33(5), 1607-1617 (2011-11-29)
The aim of this study was to develop an effective drug delivery system for the simultaneous topical delivery of two anti-inflammatory drugs, spantide II (SP) and ketoprofen (KP). To achieve this primary goal, we have developed a skin permeating nanogel
Lucas Sievens-Figueroa et al.
International journal of pharmaceutics, 423(2), 496-508 (2011-12-20)
The design and feasibility of a simple process of incorporating stable nanoparticles into edible polymer films is demonstrated with the goal of enhancing the dissolution rate of poorly water soluble drugs. Nanosuspensions produced from wet stirred media milling (WSMM) were
A Akbarian et al.
Poultry science, 93(8), 1930-1941 (2014-06-17)
Heat stress in poultry is a serious problem in many countries and has been associated with oxidative stress. Hence, nutritional interventions with antioxidants might be beneficial. Therefore, the effects of dietary Curcuma xanthorrhiza (CX) and Origanum compactum (OC) essential oils



Global Trade Item Number

SKUGTIN
09963-100G04061838658470
09963-25G04061838658487
09963-500G04061838658494