137263
Tromethamine
EMPROVE® EVOLVE
Synonym(s):
Tromethamine, Tris
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About This Item
Empirical Formula (Hill Notation):
C4H11NO3
CAS Number:
Molecular Weight:
121.14
UNSPSC Code:
12352116
MDL number:
biological source
synthetic
Quality Level
product line
EMPROVE® EVOLVE
form
powder
technique(s)
cell culture | mammalian: suitable
impurities
Endotoxin, microbial, and trace metals, tested
suitability
suitable for manufacturing use
storage temp.
2-30°C
SMILES string
NC(CO)(CO)CO
InChI
1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2
InChI key
LENZDBCJOHFCAS-UHFFFAOYSA-N
Application
Tromethamine is a commonly used biological buffer which is also referred to as Tris or Trizma. Tris as a buffer has very broad usage in diagnostics and downstream purifications. The pKa of Tris is 7.77 which corresponds closely to a physiological pH of 7.36.Tromethamine is used in biopharmaceutical buffer formulations (both upstream and downstream), electrophoresis separations and diagnostic reagent formulations. Tromethamine is especially useful in downstream purification processes.
Legal Information
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| 1372630100 | 04065267204550 |
| 1372639050 | 04065267204598 |
| 1372630003 | 04065267204543 |
| 1372635000 | 04065267204567 |
| 1372639012 | 04065267204574 |
| 1372639025 | 04065267204581 |