137276
BIS-TRIS
EMPROVE® EVOLVE
Synonym(s):
BIS-TRIS, 2,2-Bis(hydroxymethyl)-2,2′,2″-nitrilotriethanol, 2-Bis(2-hydroxyethyl)amino-2-(hydroxymethyl)-1,3-propanediol, Bis(2-hydroxyethyl)amino-tris(hydroxymethyl)methane
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About This Item
Empirical Formula (Hill Notation):
C8H19NO5
CAS Number:
Molecular Weight:
209.24
UNSPSC Code:
12161705
Beilstein/REAXYS Number:
2205275
MDL number:
biological source
synthetic
Quality Level
product line
EMPROVE® EVOLVE
form
powder
technique(s)
cell culture | mammalian: suitable
impurities
Endotoxin, microbial, and trace metals; tested
useful pH range
5.8-7.2
pKa (25 °C)
6.5
solubility
water: 0.1 M, clear, colorless
suitability
suitable for manufacturing use
storage temp.
2-30°C
SMILES string
OCCN(CCO)C(CO)(CO)CO
InChI
1S/C8H19NO5/c10-3-1-9(2-4-11)8(5-12,6-13)7-14/h10-14H,1-7H2
InChI key
OWMVSZAMULFTJU-UHFFFAOYSA-N
Application
Bis Tris is a commonly used biological buffer for very broad usage in biological systems such as diagnostics, electrophoresis and protein based bioprocessing. The pKa of Bis Tris is 6.36 which makes it a good candidate for biological-based formulations.
Bis Tris is used in a wide variety of biological applications including protein separation buffers, cell culture media, electrophoresis separations and diagnostic reagent formulations.
Bis Tris is used in a wide variety of biological applications including protein separation buffers, cell culture media, electrophoresis separations and diagnostic reagent formulations.
Legal Information
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| 13380-10G-F | 04061838729668 |
| 13380-50G-F | 04061838729675 |
| 1372769025 | 04065267205113 |
| 1372760003 | 04065267205076 |
| 1372760100 | 04065267205083 |
| 1372761000 | 04065267205090 |
| 1372769010 | 04065267205106 |