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Merck
CN

16005

Brij® L23

main component: tricosaethylene glycol dodecyl ether

Synonym(s):

Brij 35, C12E23, Polyoxyethylene (23) lauryl ether

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About This Item

CAS Number:
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12161900
MDL number:
Technical Service
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Quality Level

description

non-ionic

form

pellets

CMC

91 μM

mp

39-43 °C

HLB value

16.9

solubility

H2O: 40 mg/mL at 20 °C, clear to slightly hazy, colorless

cation traces

Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤500 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤500 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

functional group

ether, hydroxyl

SMILES string

CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

InChI

1S/C58H118O24/c1-2-3-4-5-6-7-8-9-10-11-13-60-15-17-62-19-21-64-23-25-66-27-29-68-31-33-70-35-37-72-39-41-74-43-45-76-47-49-78-51-53-80-55-57-82-58-56-81-54-52-79-50-48-77-46-44-75-42-40-73-38-36-71-34-32-69-30-28-67-26-24-65-22-20-63-18-16-61-14-12-59/h59H,2-58H2,1H3

InChI key

IEQAICDLOKRSRL-UHFFFAOYSA-N

Application

Brij® L23 is a detergent used for measuring the concentration of carbon black in lung tissues. It has also been used for selective and rapid solubilization of microbial membrane aldehyde dehydrogenase. Additionally, the product has also been used for assessing whether acrolein could lead to pro-enzyme activation by using gelatin zymography.

Biochem/physiol Actions

Brij® L23 also referred to as Brij 35 or Polyoxyethylene (23) lauryl ether is a non-ionic detergent that lowers the non-specific protein adsorption and reduces electroosmotic pumping drastically. This allows the pH to be varied without adversely affecting the flow rate. It also used as a nonionic surfactant that decreases the absorbance of the blank, inhibits turbidity as well as provides linearity.

Other Notes

Non-ionic polyoxyethylene ether. Used for selective and rapid solubilization of microbial membrane aldehyde dehydrogenase.

Legal Information

Brij is a registered trademark of Croda International PLC


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Storage Class

11 - Combustible Solids

wgk

WGK 2

ppe

dust mask type N95 (US), Eyeshields, Gloves

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2

flash_point_f

Not applicable

flash_point_c

Not applicable



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Articles

Single molecule electronics is the endeavour of constructing electronic circuitry with single molecules as the fundamental building block.


Lingling Chen et al.
Scientific reports, 7(1), 12218-12218 (2017-09-25)
Optical clearing methods can facilitate deep optical imaging in biological tissue by reducing light scattering and this has enabled accurate three-dimensional signal visualization and quantification of complex biological structures. Unfortunately, existing optical clearing approaches present a compromise between maximizing clearing
R Hommel et al.
Journal of basic microbiology, 30(4), 297-300 (1990-01-01)
An improved solubilization procedure for the membrane-bound quinoprotein aldehyde dehydrogenase from Acetobacter rancens CCM 1774 was established. After the first solubilization of membrane enzymes by Brij 35 which provided important extraction of membrane proteins other than aldehyde dehydrogenase, the application
J K Towns et al.
Analytical chemistry, 63(11), 1126-1132 (1991-06-01)
Capillary zone electrophoretic separations of proteins have been achieved by using nonionic surfactant coated capillaries. Capillaries were prepared by derivatization of the silica surface with octadecylsilane followed by the deposition of a layer of nonionic surfactant from an aqueous solution



Global Trade Item Number

SKUGTIN
16005-1KG-R04061838744951
16005-250G-F04061838744968
16005-1KG-F04061838744944
16005-25KG-R04061832489292
16005-6X1KG-R04061832489308