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275R-3

Ki-67 (MRQ-64) Rabbit Monoclonal Antibody

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About This Item

UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
MRQ-64, monoclonal
Application:
IHC (p)
Citations:
-
Technical Service
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biological source

rabbit

Quality Level

100, 500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

MRQ-64, monoclonal

description

For In Vitro Diagnostic Use in Select Regions

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (275R-34), vial of 0.1 mL concentrate Research Use Only (275R-34-RUO), vial of 0.5 mL concentrate (275R-35), vial of 1.0 mL concentrate (275R-36), vial of 1.0 mL concentrate Research Use Only (275R-36-RUO), vial of 1.0 mL pre-dilute Research Use Only (275R-37-RUO), vial of 1.0 mL pre-dilute ready-to-use (275R-37), vial of 25.0 mL pre-dilute ready-to-use (275R-30), vial of 25.0 mL pre-dilute ready-to-use Research Use Only (275R-30-RUO), vial of 7.0 mL pre-dilute ready-to-use (275R-38), vial of 7.0 mL pre-dilute ready-to-use Research Use Only (275R-38-RUO)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)

isotype

IgG

control

Burkitt lymphoma, breast (ductl carcinoma in situ), tonsil

shipped in

wet ice

storage temp.

2-8°C

visualization

nuclear

Gene Information

human ... MKI67(4288)

General description

Ki-67 (MRQ-64) is an antibody designed to target Ki-67 antigen-a nuclear protein encoded by the MKI67 gene whose presence correlates with G1, S, G2, and the mitotic phases of the cell cycle.1 Though its specific role is largely postulated and still yet to be determined, Ki-67′s presence during cellular division makes it an excellent target for labeling rapidly growing malignancies.2 Given that its presence correlates with cell proliferation, the immunohistochemical labeling of Ki-67 antigen may be useful in characterizing a lesion′s growth fraction. It has been demonstrated that identifying this antigen by IHC is useful in characterizing lesions of the breast, lymphoid cells, astrocytes, and uterus.3-9

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

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Analysis Note

United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Ki-67 Positive Control Slides, Product No. 275S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

监管及禁止进口产品

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Articles

免疫组织化学：目前在乳腺癌中的应用

免疫组织化学（免疫组化，IHC）用于表征所有组织中的细胞内蛋白质或各种细胞表面。个体标记，或更常用的各种标记蛋白质组，可用于表征各种肿瘤亚型，确定原发组织，区分转移性肿瘤和原发性肿瘤，并提供可能对预后有重要意义、预测对治疗的响应、或评估残留肿瘤后处理的其他信息。

Global Trade Item Number

SKUGTIN
275R-36-RUO04061841853619