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Merck
CN

40236

N,N-Dimethyldodecylamine N-oxide solution

~30% in H2O

Synonym(s):

DDAO, LDAO, Lauryldimethylamine N-oxide

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About This Item

Empirical Formula (Hill Notation):
C14H31NO
CAS Number:
Molecular Weight:
229.40
UNSPSC Code:
12352119
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1769927
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description

non-ionic

Quality Level

form

liquid

mol wt

229.40 g/mol

concentration

~30% in H2O

technique(s)

protein quantification: suitable

refractive index

n20/D 1.378

density

0.982 g/mL at 20 °C

SMILES string

CCCCCCCCCCCC[N+](C)([O-])C

InChI

1S/C14H31NO/c1-4-5-6-7-8-9-10-11-12-13-14-15(2,3)16/h4-14H2,1-3H3

InChI key

SYELZBGXAIXKHU-UHFFFAOYSA-N

General description

N,N-Dimethyldodecylamine N-oxide (DDAO), an amphoteric surfactant, is nonionic at high pH. The surfactant headgroup of amphoteric surfactants may carry positive and negative charges as the net charge is pH sensitive.

Application

N,N-Dimethyldodecylamine N-oxide solution has been used:
  • to examine the individual components of solvable for the extraction of few-layer graphene (FLG)and graphene oxide (GO) from complex organic matrices
  • as a component of wash buffer, elution buffer, and anion loading buffer for the purification of the double mutant reaction centers (DM RCs)
  • in the extraction of bilirubin and biliverdin by high-performance liquid chromatography (HPLC)

Biochem/physiol Actions

N,N-Dimethyldodecylamine N-oxide (DDAO) is preferred for protein studies. It is also frequently utilized for the extraction of membrane proteins.

Features and Benefits

  • Suitable for protein quantification


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pictograms

CorrosionEnvironment

signalword

Danger

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2

Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter



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Protocols

This page shows how to solubilize membrane proteins with products from Cytiva.


Karl B McCann et al.
Biologicals : journal of the International Association of Biological Standardization, 37(1), 32-36 (2008-10-25)
Human serum albumin is a well tolerated therapeutic for the treatment of hypovolemia. Despite all commercial human albumin preparations being derived from plasma, these products can have a highly variable colour. Albumin samples derived from ethanol precipitation and chromatographic fractionation
David S White et al.
eLife, 9 (2020-04-09)
Single-molecule approaches provide enormous insight into the dynamics of biomolecules, but adequately sampling distributions of states and events often requires extensive sampling. Although emerging experimental techniques can generate such large datasets, existing analysis tools are not suitable to process the
Daniel Jun et al.
STAR protocols, 3(1), 101044-101044 (2022-01-04)
The formation of defined surfaces consisting of photosynthetic reaction centers (RCs) in biohybrid solar cells is challenging. Here, we start with the production of engineered RCs for oriented binding. RCs are deposited onto gold electrodes, and 6-mercapto-1-hexanol (MCH) is used



Global Trade Item Number

SKUGTIN
40236-250ML04061831985856
40236-1L04061831985849