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42773

2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine

≥99.0% (TLC)

Synonym(s):

PC, (7R,17Z)-4-Hydroxy-N,N,N-trimethyl-9-oxo-7-[[(1-oxohexadecyl)oxy]methyl]-3,5,8-trioxa-4-phosphahexacos-17-en-1-aminium 4-oxide, inner salt, 1-Hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine, 1-Hexadecanoyl-2-(cis-9-octadecenoyl)-sn-glycero-3-phosphocholine, 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, 2-oleoyl-1-palmitoyl, L-β-Oleoyl-γ-palmitoyl-α-lecithin, PC(16:0/18:1(9Z)), PC(16:0/18:1), PC(16:0/18:1w9), POPC

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About This Item

Empirical Formula (Hill Notation):
C42H82NO8P
CAS Number:
26853-31-6
Molecular Weight:
760.08
UNSPSC Code:
51191904
NACRES:
NA.85
PubChem Substance ID:
329756267
EC Number:
248-056-7
Beilstein/REAXYS Number:
4173237
MDL number:
MFCD00043212
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biological source

synthetic

Quality Level

100

assay

≥99.0% (TLC)

form

powder

functional group

phospholipid

lipid type

phosphoglycerides

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C\CCCCCCCC

InChI

1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20+/t40-/m1/s1

InChI key

WTJKGGKOPKCXLL-RYDYYDTQSA-N

General description

Non-pyrogenic, well-defined liposomes, loaded with a molecule of choice, are formed by a single hydration step.

Application

The effect of non-ionic detergent on liposomes was studied with giant POPC liposomes. Increasing concentrations of detergent cause tubular protrusions, then indentations, to develop on spherical liposomes. At higher detergent concentrations, the liposomes burst.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCH1659
BCCF8480
BCCC1885
BCBX5069
BCBW5287

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Neil R Haria et al.
Biochimica et biophysica acta, 1838(4), 1169-1179 (2014-01-21)
Membrane fusion is critical to eukaryotic cellular function and crucial to the entry of enveloped viruses such as influenza and human immunodeficiency virus. Influenza viral entry in the host cell is mediated by a 20-23 amino acid long sequence, called
Rafael Atillo Espiritu et al.
Biochemistry, 52(14), 2410-2418 (2013-03-13)
Theonellamides (TNMs) are members of a distinctive family of antifungal and cytotoxic bicyclic dodecapeptides isolated from the marine sponge Theonella sp. Recently, it has been shown that TNMs recognize 3β-hydroxysterol-containing membranes, induce glucan overproduction, and damage cellular membranes. However, to
Rodrigo M Cordeiro
Biochimica et biophysica acta, 1838(1 Pt B), 438-444 (2013-10-08)
Reactive oxygen species (ROS) are involved in biochemical processes such as redox signaling, aging, carcinogenesis and neurodegeneration. Although biomembranes are targets for reactive oxygen species attack, little is known about the role of their specific interactions. Here, molecular dynamics simulations
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Global Trade Item Number

SKUGTIN
42773-100MG04061832104645
42773-500MG04061833248874