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Merck
CN

5133

Bovine Collagen Type I & III

from bovine hide, liquid, 10 mg/mL, suitable for cell culture, used for 3D hydrogel formation, FibriCol®

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.75
Biological source:
(Collagen solution from Bovine hide)
Form:
solution
Technique(s):
cell culture | mammalian: suitable
Assay:
>99% (SDS-PAGE Electrophoresis – Silver Stain, SDS-PAGE)
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Product Name

FibriCol®, Collagen solution from Bovine hide, 97% Type I with the remainder of Type III collagen, suitable for cell culture

biological source

(Collagen solution from Bovine hide)

Quality Level

sterility

sterile-filtered

assay

>99% (SDS-PAGE Electrophoresis – Silver Stain, SDS-PAGE)

form

solution

packaging

pkg of 20 mL

technique(s)

cell culture | mammalian: suitable

solubility

water: miscible

shipped in

wet ice

storage temp.

2-8°C

General description

FibriCol® collagen is approximately 97% Type I collagen with the remainder being comprised of Type III collagen. It contains a high monomer content as measured by gel permeation chromatography.

It is ideal for applications where high concentrations of collagen are needed. FibriCol® collagen is provided in a 20 mL volume and is contained in user-friendly packaging for use and storage. FibriCol® is sterile filtered and is supplied as a ready to use solution.

Application

FibriCol® has been used:

  • in the preparation of liposome-loaded co-gels to treat methicillin-resistant Staphylococcus aureus (MRSA) infections in vitro and in vivo
  • in the preparation of gelatin-methacrylate (gelMA)-collagen gels to study the effects of stiffness and fiber density on cellular behavior in breast cancer cell lines
  • in the preparation of collagen hydrogels to study its effects on macrophage response in partial thickness abdominal wall defect rat models

Legal Information

FibriCol is a registered trademark of Advanced BioMatrix, Inc.


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Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

低风险生物材料

This item has



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Articles

The extracellular matrix (ECM) and its attachment factor components are discussed in this article in relation to their function in structural biology and their availability for in vitro applications.


Host macrophage response to injectable hydrogels derived from ECM and ?-helical peptides
Nazia M, et al.
Acta Biomaterialia, 111, 141-152 (2020)
Raj Kumar Thapa et al.
Acta biomaterialia, 103, 115-128 (2019-12-18)
Wound infections are a significant clinical problem affecting millions of people worldwide. Topically applied antibacterial formulations with longer residence time and controlled antimicrobial release would offer significant benefits for improved prevention and treatment of infected wounds. In this study, we



Global Trade Item Number

SKUGTIN
578576-100G04061833599365
820553025004022536461267
820553902004022536660615
248487-250G04061837750717
248487-50G04061825928159
5133-20ML04061832492513
MLMIR123404061836718527
MLTUD123404061836077051