69453
L-Homocysteine
≥98.0% (NT)
Synonym(s):
(S)-2-Amino-4-mercaptobutyric acid
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Linear Formula:
HSCH2CH2CH(NH2)COOH
CAS Number:
Molecular Weight:
135.18
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
227-891-0
MDL number:
Product Name
L-Homocysteine, ≥98.0% (NT)
Quality Level
assay
≥98.0% (NT)
form
powder
optical activity
[α]/D 25.5±1.5°, c = 1 in 1 M HCl
color
white
mp
263-265 °C
application(s)
cell analysis
relevant disease(s)
Alzheimer′s disease
storage temp.
−20°C
SMILES string
N[C@@H](CCS)C(O)=O
InChI
1S/C4H9NO2S/c5-3(1-2-8)4(6)7/h3,8H,1-2,5H2,(H,6,7)/t3-/m0/s1
InChI key
FFFHZYDWPBMWHY-VKHMYHEASA-N
General description
L-homocysteine is used to diagnose homocystinuria.
Application
L-homocysteine has been used as a supplement in cell culture media.
Biochem/physiol Actions
Elevated homocysteine levels in plasma and tissue are associated with brain atrophy in Alzheimer′s disease as well as in healthy eldery subjects. Increased homocysteine is due to deficiencies in vitamin B status, specifically folate, B6 and B12 vitamins, which act as cofactors for enzymes involved in homocysteine metabolism.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Arpita Basu et al.
Atherosclerosis, 236(1), 188-195 (2014-07-27)
Plasma total homocysteine (tHcy) has been positively associated with carotid intima-media thickness (IMT) in non-diabetic populations and in a few cross-sectional studies of diabetic patients. We investigated cross-sectional and prospective associations of a single measure of tHcy with common and
Assessment of homocysteine status
Refsum H, et al.
Journal of inherited metabolic disease, 20(2), 286-294 (1997)
Ioana Cotlarciuc et al.
Stroke, 45(7), 1920-1924 (2014-05-23)
Elevated total plasma homocysteine (tHcy) levels are known to be associated with increased risk of ischemic stroke (IS). Given that both tHcy and IS are heritable traits, we investigated a potential genetic relationship between homocysteine levels and stroke risk by
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 69453-10MG | 04061832778686 |
| 69453-50MG | 04061832778846 |