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75164

4-Methylumbelliferyl oleate

Name: 4-Methylumbelliferyl oleate
Brand: SIGMA

lipase substrate, ≥95% (HPCE), solid, suitable for fluorescence

Synonym(s):

Oleic acid 4-methylumbelliferyl ester

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About This Item

Empirical Formula (Hill Notation):

C₂₈H₄₀O₄

CAS Number:

18323-58-5

Molecular Weight:

440.61

NACRES:

NA.21

PubChem Substance ID:

57652555

UNSPSC Code:

12352204

EC Number:

242-210-7

MDL number:

MFCD00076095

Beilstein/REAXYS Number:

4887028

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Properties

Product Name

4-Methylumbelliferyl oleate, suitable for fluorescence, ≥95% (HPCE)

Quality Level

100

assay

≥95% (HPCE)

form

solid

storage condition

protect from light, under inert gas

mp

37-38 °C (lit.)

solubility

2-methoxyethanol: soluble, DMSO: soluble, chloroform: soluble

fluorescence

λ_ex 312 nm in methanol, λ_ex 327 nm; λ_em 449 nm in 0.1 M phosphate pH 7.0 (lipase)

suitability

suitable for fluorescence

shipped in

wet ice

storage temp.

−20°C

SMILES string

CCCCCCCC\C=C/CCCCCCCC(=O)Oc1ccc2C(C)=CC(=O)Oc2c1

InChI

1S/C28H40O4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-27(29)31-24-19-20-25-23(2)21-28(30)32-26(25)22-24/h10-11,19-22H,3-9,12-18H2,1-2H3/b11-10-

InChI key

NKQFKJYKCVDLPT-KHPPLWFESA-N

Description

Application

4-Methylumbelliferyl oleate has been used:

as a substrate to assay the activity of non-specific esterases
to determine lipase activity
as a substrate to evaluate pancreatic lipase inhibitory activity

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Fluorogenic substrate for lipase.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Non-flavonoid phenolics from Averrhoa carambola fresh fruit

Jia X, et al.

Journal of functional foods, 32(1), 419-425 (2017)

Lipid metabolism in xanthomatous skin of hypercholesterolemic rabbits.

M L Armstrong et al.

The American journal of pathology, 125(2), 339-348 (1986-11-01)

The authors studied xanthomatous skin in cholesterol-fed rabbits for changes in lipid content and in activities of enzymes regulating intracellular lipid content. After 80 days of hypercholesterolemic diet, xanthomas were widespread and changes in lipid metabolism were marked. In both

Oleate lipase activity in Gardnerella vaginalis and reconsideration of existing biotype schemes

Moncla BJ and Pryke KM

BMC Microbiology, 9(1), 78-78 (2009)

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Global Trade Item Number

SKU	GTIN
339563-5G	04061836676841
75164-100MG	04061832899671
75164-25MG	04061832899954