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78973

Poloxamer 188, micronized

Name: Poloxamer 188, micronized
Brand: SIGMA

Synonym(s):

Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol), Lμtrol micro 68

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About This Item

CAS Number:

9003-11-6

UNSPSC Code:

12161900

NACRES:

NA.25

MDL number:

MFCD00082049

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Properties

form

powder

Quality Level

100

mol wt

~7680-9510 g/mol

composition

oxyethylene content, 79.9-83.7%

technique(s)

DNA extraction: suitable, DNA purification: suitable, NMR: suitable, RNA extraction: suitable, RNA purification: suitable

impurities

organic volatile impurities, complies (meets USP requirements), ≤0.4% total ash, ≤0.75% water, ≤1 ppm ethylene oxide, ≤20 ppm heavy metals, ≤5 ppm 1,4-dioxane, ≤5 ppm propylene oxide, 50-125 ppm butylhydroxytoluene

color

APHA: ≤100

particle size distribution

, coeff var ≤10% (residue, No. 140 USS), , coeff var ≤50% (residue, No 270 USS)

pH

5.0-7.5 (2.5% in H₂O)

suitability

complies for Infrared spectrum

SMILES string

O2C(C2)C.O1CC1

InChI

1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2

InChI key

RVGRUAULSDPKGF-UHFFFAOYSA-N

Description

Other Notes

The Poloxamer 188 grades are poloxamers from the extensive line of Pluronic^® block copolymers.

average molecular weight/mass 7680-9510 g/mol

Legal Information

Pluronic is a registered trademark of BASF

Storage Class

11 - Combustible Solids

wgk

WGK 1

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Aggregation behaviors of PEO-PPO-ph-PPO-PEO and PPO-PEO-ph-PEO-PPO at an air/water interface: experimental study and molecular dynamics simulation.

Houjian Gong et al.

Langmuir : the ACS journal of surfaces and colloids, 28(38), 13590-13600 (2012-09-08)

The block polyethers PEO-PPO-ph-PPO-PEO (BPE) and PPO-PEO-ph-PEO-PPO (BEP) are synthesized by anionic polymerization using bisphenol A as initiator. Compared with Pluronic P123, the aggregation behaviors of BPE and BEP at an air/water interface are investigated by the surface tension and

Combined pluronic P85- and ultrasound contrast agents-mediated gene transfection to HepG2 cells.

Xijun Zhang et al.

Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 31(6), 842-845 (2011-12-17)

This study examined the effect of P85 (a pluronic block copolymer) and microbubble (MB) ultrasound contrast agents under ultrasound irradiation on gene transfection and expression. The pEGFP plasmids that can encode enhanced green fluorescent protein (pEGFP) served as a report

A computer Time Trade-Off: a feasible and reliable alternative for the interview Time Trade-Off in rheumatoid arthritis.

Laurien Buitinga et al.

Clinical and experimental rheumatology, 29(5), 783-789 (2011-10-04)

The Time Trade-Off (TTO) is an instrument used for valuing health-related quality of life. This study evaluated the test-retest reliability of a computer TTO in rheumatoid arthritis (RA), and compared the computer with the interview TTO regarding feasibility and agreement.

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Global Trade Item Number

SKU	GTIN
78973-1KG	04061832947556