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Merck
CN

84797

Poly(ethylene glycol)

greener alternative

BioUltra, 2,000

Synonym(s):

Polyethylene glycol, PEG

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About This Item

Linear Formula:
H(OCH2CH2)nOH
CAS Number:
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352104
MDL number:
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Quality Level

product line

BioUltra

form

powder

mol wt

Mr 1900-2200

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

impurities

insoluble matter:, passes filter test, ≤0.001% peroxides (as H2O2):

pH

5.5-7.0 (25 °C, 50 mg/mL in H2O)

mp

50-53 °C

solubility

H2O: 50 mg/mL at 25 °C, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤200 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤200 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg

λ

50 mg/mL in H2O

UV absorption

λ: 260 nm Amax: ≤0.1, λ: 280 nm Amax: ≤0.04

greener alternative category

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

General description

Poly(ethylene glycol) (PEG) is a non-ionic hydrophilic polymer and is available in different molecular weights. It helps in the purification and crystal growth of proteins and nucleic acids. PEG and dextran together result in aqueous polymer two phase system, which is required for the purification of biological materials. PEG also interacts with cell membrane, thereby allowing cell fusion. It exhibitsstealth effect, prolonged blood circulation and excellent biocompatibility. PEG has an ability to elicit hypersensitivity reactions via stimulating complement pathway.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

Application

Poly(ethylene glycol) has been used:
  • as a constituent in the preparation of liquid desiccant solutions
  • as a precipitating agent and additive in protein crystallization
  • as a representative biocompatible polymer to decipher its interactions with cellular system at molecular level



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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

281.5 °F - closed cup

flash_point_c

138.6 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)



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Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target
Zhang B, et al.
Cell, 176(3), 636-648 (2019)
Poly(Ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications (2013)
Exploring carbon nanomaterial diversity for nucleation of protein crystals
Govada L, et al.
Scientific Reports, 6(18), 20053-20053 (2016)



Global Trade Item Number

SKUGTIN
142905-250MG04061838734532
84797-250G-F04061833008133
84797-1KG-F04061833008126