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85580

Spermidine trihydrochloride

From microbial,synthetic, ≥99.0% (AT), nNos inhibitor, powder

Synonym(s):

N-(3-Aminopropyl)-1,4-butanediamine trihydrochloride

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About This Item

Linear Formula:
NH2(CH2)3NH(CH2)4NH2 · 3HCl
CAS Number:
334-50-9
Molecular Weight:
254.63
NACRES:
NA.77
PubChem Substance ID:
329769390
UNSPSC Code:
12352204
EC Number:
206-379-0
MDL number:
MFCD00012918
Beilstein/REAXYS Number:
3552356
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Product Name

Spermidine trihydrochloride, ≥99.0% (AT)

Quality Level

200

biological source

microbial, synthetic

assay

≥99.0% (AT)

form

powder

mp

~250 °C (dec.), 257-259 °C (lit.)

solubility

H2O: 0.1 g/mL, clear, colorless

storage temp.

room temp

SMILES string

Cl[H].Cl[H].Cl[H].NCCCCNCCCN

InChI

1S/C7H19N3.3ClH/c8-4-1-2-6-10-7-3-5-9;;;/h10H,1-9H2;3*1H

InChI key

LCNBIHVSOPXFMR-UHFFFAOYSA-N

General description

Spermidine is a polyamine and a trivalent organic cation.

Application

Spermidine trihydrochloride has been used as standard for the detection of biogenic amines using HPLC.

Biochem/physiol Actions

Spermidine modulates various cellular activities like cellular development and differentiation, stability of DNA and apoptosis.
Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; Stimulates T4 polynucleotide kinase activity.
Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity.

Disclaimer

Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG3320
BCCC7694
BCCB0592
BCBV9936
BCBS0952V

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Articles

感应染料

一氧化氮 (NO) 是神经元、内皮细胞和免疫系统中的信号转运分子。

Sensor Dyes

Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.

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Global Trade Item Number

SKUGTIN
85580-25G04061833415986
85580-5G04061833354766