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Merck
CN

A2562

Angiotensinogen from human plasma

≥80% (SDS-PAGE)

Synonym(s):

Hypertensinogen, Renin substrate

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About This Item

CAS Number:
UNSPSC Code:
12352202
NACRES:
NA.26
MDL number:
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Product Name

Angiotensinogen from human plasma, ≥80% (SDS-PAGE), lyophilized powder

Quality Level

assay

≥80% (SDS-PAGE)

form

lyophilized powder

color

white

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... AGT(183)

Biochem/physiol Actions

Angiotensinogen (renin substrate), a component of the rennin-angiotensin system, is a precursor protein to a family of blood pressure and hormone release regulating peptides known as the angiotensins.

Packaging

Package size based on protein content.

Physical form

Lyophilized powder containing sodium phosphate buffer, pH 7.

Analysis Note

Protein determined by A1%/280

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

高风险级别生物产品--人源产品

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Articles

脂肪组织中的胰岛素耐受性减少了循环游离脂肪酸的摄入,并增加了脂肪酶对储存甘油三酯的水解。了解与胰岛素耐受性相关的激素、细胞因子和脂肪因子。

Lipid Induced Insulin Resistance


D A Tewksbury
Federation proceedings, 42(10), 2724-2728 (1983-07-01)
Human angiotensinogen has been purified from outdated blood bank plasma. The purified angiotensinogen has a specific angiotensin I (Ang I) content of 20.7 micrograms Ang I/mg protein and contains only one amino-terminal amino acid, aspartic acid. However, it exhibits two
Weijian Shao et al.
American journal of physiology. Renal physiology, 304(5), F505-F514 (2013-01-11)
In angiotensin II (ANG II) infusion hypertension, there is an augmentation of intratubular angiotensinogen (AGT) and ANG II leading to increased urinary AGT and ANG II excretion rates associated with tissue injury. However, the changes in urinary AGT and ANG
The renal angiotensin system does not reveal its secrets with a cross-sectional analysis of urinary angiotensinogen levels.
Branko Braam
Journal of hypertension, 31(4), 840-840 (2013-03-08)



Global Trade Item Number

SKUGTIN
A2562-.1MG04061832818887