A3286
N-Acetyl-D-glucosamine
BioReagent, suitable for cell culture
Synonym(s):
2-Acetamido-2-deoxy-D-glucose, D-GlcNAc
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About This Item
Empirical Formula (Hill Notation):
C8H15NO6
CAS Number:
Molecular Weight:
221.21
UNSPSC Code:
12352201
NACRES:
NA.75
PubChem Substance ID:
EC Number:
231-368-2
Beilstein/REAXYS Number:
1727589
MDL number:
product line
BioReagent
Quality Level
assay
≥95% (HPLC)
form
powder
technique(s)
cell culture | mammalian: suitable
mp
211 °C (dec.) (lit.)
application(s)
advanced drug delivery
storage temp.
−20°C
SMILES string
CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
InChI
1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8?/m1/s1
InChI key
OVRNDRQMDRJTHS-RTRLPJTCSA-N
General description
N-Acetylglucosamine (GlcNAc), a derivative of glucose is a monosaccharide. It is a white powder and is mildly sweet. It melts at 221°C. GlcNAc is 25% soluble in water. It is present in bromelain, ricin agglutinin and abrus agglutinin, in plants. In humans, it is present in tissue plasminogen activator, growth factors and hormones.
Application
N-Acetyl-D-glucosamine addition has been used:
- as a substrate to develop dot-blots
- as a substrate to reveal alkaline phosphatase in the immunohistochemical analysis
- to detect specific immune complexes in western blot analysis
Biochem/physiol Actions
N-Acetylglucosamine (GlcNAc) oligomer may have the ability to initiate factors for canine polymorphonuclear cells (PMN) in vivo. It possesses wound healing and chemotactic activity. GlcNAc and its derivatives are usually employed in preparing dietary supplements and also used in therapeutic development.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Glycoprofiling effects of media additives on IgG produced by CHO cells in fed-batch bioreactors
Kildegaard H F, et al.
Biotechnology and Bioengineering, 113(2), 359-366 (2016)
Effect of N-acetyl-d-glucosamine and d-glucosamine oligomers on canine polymorphonuclear cells in vitro
Usami Y, et al.
Carbohydrate Polymers, 36(2-3), 137-141 (1998)
Glucose metabolism and hexosamine pathway regulate oncogene-induced senescence
Gitenay D, et al.
Cell Death & Disease, 5(2), e1089-e1089 (2014)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| A3286-5G | 04061833360620 |
| A3286-100G | 04061833360613 |
| A3286-25G | 04061835522552 |