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Merck
CN

A5751

Acetylthiocholine iodide

≥98% (TLC), powder or crystals

Synonym(s):

(2-Mercaptoethyl)trimethylammonium iodide acetate

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About This Item

Linear Formula:
CH3COSCH2CH2N(CH3)3I
CAS Number:
Molecular Weight:
289.18
UNSPSC Code:
12352204
NACRES:
NA.83
PubChem Substance ID:
EC Number:
217-474-1
Beilstein/REAXYS Number:
3916578
MDL number:
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Quality Level

assay

≥98% (TLC)

form

powder or crystals

color

white

mp

205-210 °C (lit.)

solubility

H2O: 100 mg/mL

storage temp.

2-8°C

SMILES string

[I-].CC(=O)SCC[N+](C)(C)C

InChI

1S/C7H16NOS.HI/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1

InChI key

NTBLZMAMTZXLBP-UHFFFAOYSA-M

General description

Acetylcholinesterase substrate and nicotinic acetylcholine receptor agonist.

Application

Acetylthiocholine iodide has been used as a substrate in the preparation of acetylcholine esterase (AChE) assay working solution for AChE activity assay. It has also been used as a component in phosphate buffer (PB) for cholinesterase assay.
Substrate for the colorimetric determination of acetylcholinesterase activity.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.


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wgk

WGK 3

pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges



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Effect of short-term exposure to chlorpyrifos on developmental parameters and biochemical biomarkers in Chironomus riparius Meigen
Callaghan A, et al.
Ecotoxicology and Environmental Safety, 50(1), 19-24 (2001)
Anti-acetylcholinesterase activities of traditional Chinese medicine for treating Alzheimer's disease
Lin HQ, et al.
Chemico-Biological Interactions, 175(1-3), 352-354 (2008)
The exosome secretory pathway transports amyloid precursor protein carboxyl-terminal fragments from the cell into the brain extracellular space
Perez GR, et al.
The Journal of Biological Chemistry, 287(51), 43108-43115 (2012)



Global Trade Item Number

SKUGTIN
A5751-25G04061833376294
A5751-1G04061835553501
A5751-250MG04061833376287
A5751-5G04061835553518