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Merck
CN

A6661

Albumin, dinitrophenyl

lyophilized powder

Synonym(s):

DNP-albumin human

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About This Item

CAS Number:
UNSPSC Code:
12352202
NACRES:
NA.25
MDL number:
eCl@ss:
42010201
Biological source:
human
Form:
lyophilized powder
Technique(s):
RNA extraction: suitable
Impurities:
Infectious agents, tested
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biological source

human

Quality Level

form

lyophilized powder

extent of labeling

30-40 mol DNP per mol albumin

technique(s)

RNA extraction: suitable

impurities

Infectious agents, tested

UniProt accession no.

storage temp.

2-8°C

SMILES string

FC(F)(F)C(F)(F)C(F)(F)F

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11

InChI key

QYSGYZVSCZSLHT-UHFFFAOYSA-N

Gene Information

human ... ALB(213)

Application

Albumin, dinitrophenyl has been used to assess degranulation from rat mast cells by treatment of:
  • bakkenolide B
  • 4-Hydroxy-2-(4-hydroxyphenethyl)isoindoline-1,3-dione (PD1)
  • mifepristone
Used for detection in immunological analyses. Can be used as an immunological challenge to activate basophils via the IgE receptor.

Analysis Note

Source material has tested negative for HIV and HBsAg


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

高风险级别生物产品--人源产品

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Carolin N Zorn et al.
Scientific reports, 8(1), 15467-15467 (2018-10-21)
Antigen (Ag)-mediated crosslinking of IgE-loaded high-affinity receptors for IgE (FcεRI) on mast cells (MCs) triggers activation of proinflammatory effector functions relevant for IgE-associated allergic disorders. The cytosolic tyrosine kinase BTK and the SH2-containing inositol-5'-phosphatase SHIP1 are central positive and negative
Little, S.R. and Eisen, H.N.
Methods Immunol. Immunochem., 1, 128-128 (1967)
Xuan Che et al.
International journal of medical sciences, 17(2), 224-233 (2020-02-11)
Background: Adenomyosis is a quite common gynecological disorder and above 30% of patients have typical secondary and progressive dysmenorrhea. Current treatments still have many disadvantages and thereby the novel treatment aiming to relieve dysmenorrhea still needs to be further investigated.



Global Trade Item Number

SKUGTIN
A6661-100MG04061833382615