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A8973

2-Arachidonyl glycerol

≥98% (HPLC), Endogenous cannabinoid receptor agonist, solution

Synonym(s):

(all-Z)-5,8,11,14-Eicosatetraenoic acid 2-hydroxy-1-(hydroxymethyl)ethyl ester, 2-AG, 2-Arachidonoylglycerol, 2-Monoarachidonoylglycerol

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About This Item

Empirical Formula (Hill Notation):
C23H38O4
CAS Number:
53847-30-6
Molecular Weight:
378.55
UNSPSC Code:
12352200
PubChem Substance ID:
24891388
NACRES:
NA.77
MDL number:
MFCD01862600
Assay:
≥98% (HPLC)
Form:
solution
Quality level:
100
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Product Name

2-Arachidonyl glycerol, ~10 mg/mL, ≥98% (HPLC)

description

9:1 mixture of 2-AG and 1-AG

Quality Level

100

assay

≥98% (HPLC)

form

solution

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

concentration

~10 mg/mL

shipped in

wet ice

storage temp.

−20°C

SMILES string

[H]C(CO)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)CO

InChI

1S/C23H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(26)27-22(20-24)21-25/h6-7,9-10,12-13,15-16,22,24-25H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-

InChI key

RCRCTBLIHCHWDZ-DOFZRALJSA-N

Gene Information

human ... FAAH(2166)
rat ... Cnr1(25248), Cnr2(57302)

Biochem/physiol Actions

Endogenous cannabinoid receptor agonist.

Physical form

acetonitrile solution

Disclaimer

Air sensitive

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

35.6 °F - closed cup

flash_point_c

2 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

危险化学品

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Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
057M4715V
056M4727V
085M4714V
024M4742V
013M4714V

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Progress in lipid research, 45(5), 405-446 (2006-05-09)
2-Arachidonoylglycerol (2-AG) is a unique molecular species of monoacylglycerol isolated in 1995 from rat brain and canine gut as an endogenous ligand for the cannabinoid receptors. 2-AG is rapidly formed from arachidonic acid-containing phospholipids through increased phospholipid metabolism, such as
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Anandamide and 2-arachidonoylglycerol (2-AG) are the two main endocannabinoids, exerting their effects by activating type 1 (CB1r) and type 2 (CB2r) cannabinoid receptors. Anandamide inhibits anxiety-like responses through the activation of CB1r in certain brain regions, including the dorsolateral periaqueductal
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Global Trade Item Number

SKUGTIN
A8973-5MG04061833401033