Key Documents

View All Documentation

B1155

bisBenzimide H 33258

Name: bisBenzimide H 33258
Brand: SIGMA

≥98% (HPLC and TLC), Bcl-XL inhibitor, powder

Synonym(s):

2′-(4-Hydroxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5′-bi(1H-benzimidazole) trihydrochloride, 2-[2-(4-Hydroxyphenyl)-6-benzimidazoyl]-6-(1-methyl-4-piperazyl)benzimidazole trihydrochloride, BBIH, BXI-72, HOE 33258, Hoechst 33258, NSC334072

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₂₅H₂₄N₆O · 3HCl

CAS Number:

23491-45-4

Molecular Weight:

533.88

NACRES:

NA.77

PubChem Substance ID:

24891565

UNSPSC Code:

41106305

EC Number:

245-690-6

MDL number:

MFCD00012679

Beilstein/REAXYS Number:

4088183

Assay:

≥98% (HPLC and TLC)

Form:

powder

Quality level:

200

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Product Name

bisBenzimide H 33258, powder, BioReagent, suitable for cell culture, ≥98% (HPLC and TLC)

product line

BioReagent

Quality Level

200

assay

≥98% (HPLC and TLC)

form

powder

technique(s)

cell culture | mammalian: suitable

solubility

H₂O: 10 mg/mL, water and ethanol: 10 mg/mL

suitability

passes application test for fluorescence

storage temp.

−20°C

SMILES string

Cl[H].Cl[H].Cl[H].[H]O[H].CN1CCN(CC1)c2ccc3NC(=NCc3c2)c4ccc5NC(=NCc5c4)c6ccc(O)cc6

InChI

1S/C27H28N6O.3ClH.H2O/c1-32-10-12-33(13-11-32)22-5-9-25-21(15-22)17-29-27(31-25)19-4-8-24-20(14-19)16-28-26(30-24)18-2-6-23(34)7-3-18;;;;/h2-9,14-15,34H,10-13,16-17H2,1H3,(H,28,30)(H,29,31);3*1H;1H2

InChI key

OWRSPPSBNWJJAR-UHFFFAOYSA-N

Description

Application

bisBenzimide H 33258 is useful for staining DNA, chromosomes and nuclei. bisBenzimide H 33258 may be used for fluorescence microscopy or flow cytometry.
Excitation max. = 346 nm
Emission max. = 460 nm

bisBenzimide H 33258 is useful for staining DNA, chromosomes, and nuclei. May be used for fluorescence microscopy or flow cytometry.

Biochem/physiol Actions

bisBenzimide H 33258 is a potent and selective Bcl-XL inhibitor.

bisBenzimide H 33258 is a potent and selective Bcl-XL inhibitor. bisBenzimide H 33258 is a membrane-permeable, fluorescent DNA stain with low cytotoxicity that intercalate in A-T regions of DNA.

Still not finding the right product?

Explore all of our products under bisBenzimide H 33258

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

细胞培养中的支原体检测和清除

通过PCR法、DNA染色法和培养法检测细胞培养中的支原体污染。探索我们的支原体预防、清除和检测试剂盒。

良好的细胞库操作实践

用于细胞系冷冻保存的良好细胞库操作实践概述。

细胞培养中的质量控制注意事项

用于维持高质量经验证的无污染细胞培养的质量控制指南。免费下载ECACC手册。

View All Articles

Mitochondrial distribution and activity in human mature oocytes: gonadotropin-releasing hormone agonist versus antagonist for pituitary down-regulation.

Maria Elena Dell'Aquila et al.

Fertility and sterility, 91(1), 249-255 (2008-03-28)

To analyze the effects of GnRH agonists versus antagonists on mitochondrial distribution and activity in human mature oocytes. Randomized research experimental study. Academic basic research laboratory and hospital-based fertility center. Two hundred twenty-five supernumerary mature oocytes from 44 patients. Fluorescent

Purification of proteins from baculovirus-infected insect cells.

Luke O'Shaughnessy et al.

Methods in molecular biology (Clifton, N.J.), 681, 295-309 (2010-10-28)

Expression of recombinant proteins in the baculovirus/insect cell expression system is employed because it enables post-translational protein modification and high yields of recombinant protein. The system is capable of facilitating the functional expression of many proteins - either secreted or

Mitochondrial distribution patterns in canine oocytes as related to the reproductive cycle stage.

Luisa Valentini et al.

Animal reproduction science, 117(1-2), 166-177 (2009-04-18)

This study investigates the mitochondrial (mt) distribution in canine ovarian oocytes examined at recovery time, as related to the reproductive cycle stage, and in oviductal oocytes. Ovarian Germinal Vesicle (GV) stage oocytes were recovered from bitches in anestrous (A, n=2)

View All Related Papers

Global Trade Item Number

SKU	GTIN
B1155-100MG	04061833421277
B1155-25MG	04061833421352