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Merck
CN

B1502

Brain Extract from bovine brain

Type I, Folch Fraction I

Synonym(s):

Brain Extract from Bovine

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About This Item

NACRES:
NA.25
UNSPSC Code:
12352211
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biological source

bovine brain

Quality Level

type

Type I

form

powder

lipid type

phosphoglycerides

storage temp.

−20°C

General description

Brain extract has lipids, especially polyunsaturated fatty acids (PUFAs) at high level. Extract from substantia niagra and the striatum has high amount of iron.

Application

Brain Extract from bovine brain has been used:
  • to prepare small unilamellar vesicles
  • in lipid binding assay
  • to aid the recovery of phosphoinositides and also to terminate the reaction in phosphatidylinositol 5-phosphate (PtdIns5P) and PtdIns4P assay
  • in liposome and protein self-aggregation assays

Biochem/physiol Actions

Brain lipids are involved in cellular signal transduction, membrane organization, trafficking protein modification, interactions and energy storage.

Packaging

Sealed ampule.

Other Notes

Contains phosphatidylinositol phosphatidylserine,other brain lipids.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Cholesterol and Fat Metabolism in Alzheimer?s Disease
Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders, 161-193 (2017)
Measurement of phosphoinositides in the zebrafish Danio rerio
Jones DR, et al.
Nature Protocols, 8(6), 1058-1058 (2013)
Lipid binding regulates synaptic targeting of PICK1, AMPA receptor trafficking, and synaptic plasticity
Jin W, et al.
The Journal of Neuroscience, 26, 2380-2390 (2006)



Global Trade Item Number

SKUGTIN
B1502-1G04061826656310
B1502-100MG04061832793450
B1502-25MG04061832793467