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B1552

Bromoenol lactone

≥98% (TLC)

Synonym(s):

BEL, E-6-(Bromoethylene)tetrahydro-3-(1-naphthyl)-2H-pyran-2-one

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About This Item

Empirical Formula (Hill Notation):
C16H13BrO2
CAS Number:
88070-98-8
Molecular Weight:
317.18
NACRES:
NA.77
PubChem Substance ID:
24278257
UNSPSC Code:
41106300
MDL number:
MFCD00270871
Assay:
≥98% (TLC)
Form:
powder
Quality level:
200
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biological source

synthetic (organic)

Quality Level

200

assay

≥98% (TLC)

form

powder

potency

636 nM Ki

solubility

DMSO: soluble (Dilute in aqueous medium immediately prior to use and store on ice for no more than 12 hours.), degassed ethanol: soluble (Dilute in aqueous medium immediately prior to use and store on ice for no more than 12 hours.)

λmax

224 nm

storage temp.

−20°C

SMILES string

[H]\C(Br)=C1\CCC(C(=O)O1)c2cccc3ccccc23

InChI

1S/C16H13BrO2/c17-10-12-8-9-15(16(18)19-12)14-7-3-5-11-4-1-2-6-13(11)14/h1-7,10,15H,8-9H2/b12-10+

InChI key

BYUCSFWXCMTYOI-ZRDIBKRKSA-N

Biochem/physiol Actions

Potent, irreversible inhibitor of calcium-independent phospholipase A2 and of magnesium-dependent phosphatidate phosphohydrolase from P388D macrophages (IC50 = 8 μM); enzyme activated irreversible chymotrypsin inhibitor (Ki = 636 nM).

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SLCK6607
SLCH7859
SLCF8840
SLBZ0449
SLBW2670

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Articles

Chymotrypsin

Analytical Enzyme Chymotrypsin: Chymotrypsin is produced in the acinar cells of the pancreas as the inactive precursor, chymotrypsinogen.

Franz J Ricken et al.
PLoS neglected tropical diseases, 11(5), e0005636-e0005636 (2017-05-26)
Alveolar echinococcosis (AE) is caused by the metacestode stage of Echinococcus multilocularis. The inflammatory response to this infection is influenced by the interaction of the parasite with the host. We aimed to analyze human liver lesions infected with Echinococcus multilocularis
C D Eiber et al.
Vision research, 151, 41-52 (2017-11-14)
The "blue-on" and "blue-off" receptive fields in retina and dorsal lateral geniculate nucleus (LGN) of diurnal primates combine signals from short-wavelength sensitive (S) cone photoreceptors with signals from medium/long wavelength sensitive (ML) photoreceptors. Three questions about this combination remain unresolved.
Sunbin Ling et al.
Molecular oncology, 11(6), 682-695 (2017-04-19)
Drug treatments for hepatocellular carcinoma (HCC) often fail because of multidrug resistance (MDR). The mechanisms of MDR are complex but cancer stem cells (CSCs), which are able to self-renew and differentiate, have recently been shown to be involved. The deubiquitinating
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Global Trade Item Number

SKUGTIN
B1552-5MG04061833258651