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Merck
CN

C2624

Carbonic Anhydrase from bovine erythrocytes

≥95% (SDS-PAGE), specific activity ≥3,500 W-A units/mg protein, lyophilized powder

Synonym(s):

Carbonic Anhydrase from bovine erythrocytes, Carbonate Dehydratase, Carbonate Hydrolyase

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About This Item

CAS Number:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-576-6
MDL number:
EC Number:
Specific activity:
≥3,500 W-A units/mg protein
Assay:
≥75% protein basis (biuret), ≥95% (SDS-PAGE)
Biological source:
bovine erythrocytes
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biological source

bovine erythrocytes

Quality Level

assay

≥75% protein basis (biuret), ≥95% (SDS-PAGE)

form

lyophilized powder

specific activity

≥3,500 W-A units/mg protein

solubility

deionized water: >10 mg/mL

storage temp.

2-8°C

Application

Carbonic anhydrase, from bovine erythrocytes, is used to create carbon dioxide capture systems and to research various purification techniques . Carbonic anhydrase is also used to study acid-base regulation in fish and carbonic anhydrase type II deficiency syndrome .

Biochem/physiol Actions

Carbonic Anhydrase is a zinc-containing enzyme that catalyzes the reversible conversion of carbon dioxide to bicarbonate. One of its main physiological roles is to maintain the acid-base balance in blood and other tissues. Lack of carbonic anhydrase results in carbonic anhydrase type II deficiency syndrome, which is an autosomal recessive disease that causes osteopetrosis, renal tubular acidosis and brain calcifications .

Other Notes

One Wilbur-Anderson (W-A) unit will cause the pH of a 0.02 M Trizma buffer to drop from 8.3 to 6.3 per min at 0°C. (One W-A unit is essentially equivalent to one Roughton-Booth unit.)


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pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

低风险生物材料
动植物源性产品

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Joana da Costa Ores et al.
Chemosphere, 88(2), 255-259 (2012-04-20)
This work presents a study of industrially applicable techniques to obtain a biologically supported carbon dioxide capture system, based on the extraction of carbonic anhydrase from bovine blood. Carbonic anhydrase is a metalloenzyme which catalyzes the reversible hydration of carbon
K M Gilmour et al.
The Journal of experimental biology, 212(Pt 11), 1647-1661 (2009-05-19)
Carbonic anhydrase (CA) is the zinc metalloenzyme that catalyses the reversible reactions of CO(2) with water. CA plays a crucial role in systemic acid-base regulation in fish by providing acid-base equivalents for exchange with the environment. Unlike air-breathing vertebrates, which
Thomas M Bosley et al.
Brain : a journal of neurology, 134(Pt 12), 3502-3515 (2011-11-29)
Carbonic anhydrase type II deficiency syndrome is an uncommon autosomal recessive disease with cardinal features including osteopetrosis, renal tubular acidosis and brain calcifications. We describe the neurological, neuro-ophthalmological and neuroradiological features of 23 individuals (10 males, 13 females; ages at



Global Trade Item Number

SKUGTIN
C2624-100MG04061833484319
C2624-500MG04061833484326